General Anesthetics Flashcards
List all the inhaled anesthetics
N2O halothane enflurane isoflurane desflurane sevoflurane methoxyflurane HIS MED
List all the IV anesthetics
barbituates
propofol
ketamine
etomidate
Define the MAC
concentration that results in IMMOBILITY in 50% of paitents when exposed to a noxious stimulus such as surgical incision
IMMOBILITY MAC
Low MAC = ?
high MAC = ?
low MAC (requires little of the substance to make people not move when they feel pain) = potent` high MAC = low potency
how do you measure the potency of an anesthetic?
liposolubity ie a high oil:gas partition coefficient bc htat means more of it is lovin the fatty oil
Two measurements of potency adn their relationship
increased oil: gas = low MAC = POTENT
blood:gas parittion coefficient measures?
latency to onset
HIGH - later onset
LOW - quicker onset
anesthetics with a large oil:gas have a large blood:gas
yep. thats a thing.
how does ventilation affect arterial tension of anesthetic
if have a low blood:gas then will cause only slight increased in arterial tension
if have a high blood: gas then will cause a sig increase in arterial tension
What determines the ateriovenous concentration gradient?
depents on the uptake at the tissue, and slows down the onset
Elimination for low blood and tissue solubility
mirrors anesthetic: easy transport in and out
elimination for high blood and tissue solubility
depends on duration of anesthetic - bc gotta get ride of all the anesthetic in the blood and tissues that has been shoved in there the whole time
~*~Which inhaled anesthetics cause decreased BP due to affects on myocardium
halothane
enflurane
~*~Which inhaled anesthetisc cause decreasedp BP due to affects of TPR?
isoflurane
desfulrane
sevoflurane
~*~Which inhaled anesthetics are preferred in peopel with heart problems?
isoflurane
desflurane
sevoflurane
bc dont affecy myometrium
