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Biochem Human Form and Function > Oxidative phosphorylation German 9/22/16 > Flashcards

Oxidative phosphorylation German 9/22/16 Flashcards

1
Q

Where does oxidative phosphorylation occur?

A

The inner membrane of the mitochondria

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2
Q

How many complexes are in the Electron transport chain?

A

four

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3
Q

What are three ways to transfer electrons in the electron transport chain?

A
  • Direct electron
  • Hydrogen atom
  • Hydride Ion
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4
Q

What are three electron carriers found inside the Electron transport chain?

A
  • Ubiquinone
  • Cytochromes
  • Iron-sulfur proteins
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5
Q

Which electron carrier can carry both electrons and protons?

A

Ubiquinone

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6
Q

Which electron carrier is lipid soluble and membrane mobile?

A

Ubiquinone

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7
Q

Which electron carrier has three types: a,b,c?

A

Cytochromes

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8
Q

Which electron carrier is classified by light absorption?

A

Cytochromes

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9
Q

Which electron carrier only accepts electrons and is mobile?

A

Cytochrome c

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10
Q

Which electron carriers only accept electrons?

A

Cytochromes

Iron-Sulfur proteins

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11
Q

What ETC complex is called NADH dehydrogenase?

A

Complex I

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12
Q

What ETC complex is called Succinate dehydrogenase?

A

Complex II

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13
Q

What is unique to complex II?

A

FADH2 goes here

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14
Q

What complexes in the ETC does H+ get pumped through?

A

I
III
IV

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15
Q

What happens in complex I?

A

NADH loses electrons and H+ and becomes NAD+

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16
Q

Where does the electron taken from NADH go in complex I?

A

Ubiquinone

17
Q

What electron carrier moves from complex III to complex IV?

A

Cytochrome C

18
Q

What two complexes introduce electrons in the ETC?

A

Complex I

Complex II

19
Q

What is the Q cycle?

A

It is found in Complex III

Ubiquinone moves electrons to cytochrome c

20
Q

What happens in the Q cycle?

A

The ubiquinone releases one electron onto cytochrome c and keeps one to become a free radical

21
Q

What eventually happens to the free radical ubiquinone from the Q cycle?

A

The ubiquinone joins with another free radical ubiquinone

22
Q

What is the main function of complex III?

A

Transfer electrons to cytochome c

23
Q

What is the main function of complex IV?

A

Transports hydrogen

Reduce Oxygen

24
Q

What does the ATP synthase use to move and create ATP?

A

H+

25
Q

T/F ATP is transported out of the mitochondria

A

True

26
Q

What are two shuttle systems that allow glycolysis NADH to affect the ETC?

A

Malate-aspartate

Glycerol 3-phosphate

27
Q

Where does the malate-asparate shuttle occur?

A

Liver
Heart
Kidney

28
Q

Where does the glycerol 3-phosphate shuttle occur?

A

Brain

Skeletal Muscle

29
Q

What two conditions favor ROS formation?

A
  • Mitochondria not making ATP (Lock of O2 or ADP)

- Excess NADH

Biochem Human Form and Function (28 decks)

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