Oxidative phosphorylation German 9/22/16 Flashcards
Where does oxidative phosphorylation occur?
The inner membrane of the mitochondria
How many complexes are in the Electron transport chain?
four
What are three ways to transfer electrons in the electron transport chain?
- Direct electron
- Hydrogen atom
- Hydride Ion
What are three electron carriers found inside the Electron transport chain?
- Ubiquinone
- Cytochromes
- Iron-sulfur proteins
Which electron carrier can carry both electrons and protons?
Ubiquinone
Which electron carrier is lipid soluble and membrane mobile?
Ubiquinone
Which electron carrier has three types: a,b,c?
Cytochromes
Which electron carrier is classified by light absorption?
Cytochromes
Which electron carrier only accepts electrons and is mobile?
Cytochrome c
Which electron carriers only accept electrons?
Cytochromes
Iron-Sulfur proteins
What ETC complex is called NADH dehydrogenase?
Complex I
What ETC complex is called Succinate dehydrogenase?
Complex II
What is unique to complex II?
FADH2 goes here
What complexes in the ETC does H+ get pumped through?
I
III
IV
What happens in complex I?
NADH loses electrons and H+ and becomes NAD+
Where does the electron taken from NADH go in complex I?
Ubiquinone
What electron carrier moves from complex III to complex IV?
Cytochrome C
What two complexes introduce electrons in the ETC?
Complex I
Complex II
What is the Q cycle?
It is found in Complex III
Ubiquinone moves electrons to cytochrome c
What happens in the Q cycle?
The ubiquinone releases one electron onto cytochrome c and keeps one to become a free radical
What eventually happens to the free radical ubiquinone from the Q cycle?
The ubiquinone joins with another free radical ubiquinone
What is the main function of complex III?
Transfer electrons to cytochome c
What is the main function of complex IV?
Transports hydrogen
Reduce Oxygen
What does the ATP synthase use to move and create ATP?
H+
T/F ATP is transported out of the mitochondria
True
What are two shuttle systems that allow glycolysis NADH to affect the ETC?
Malate-aspartate
Glycerol 3-phosphate
Where does the malate-asparate shuttle occur?
Liver
Heart
Kidney
Where does the glycerol 3-phosphate shuttle occur?
Brain
Skeletal Muscle
What two conditions favor ROS formation?
- Mitochondria not making ATP (Lock of O2 or ADP)
- Excess NADH
