Citric Acid Cycle Enzymes and Products German 9/22/16 Flashcards
What is the first step of the Citric Acid Cycle (CAC)?
Go from Acetyl-CoA + oxaloacetate to Citrate
What enzyme is responsible for converting Acetyl-CoA + oxaloacetate to Citrate?
Citrate synthase
What is the second step of the CAC?
Go from Citrate to Isocitrate
What enzyme is responsible for converting citrate to isocitrate?
aconitase
What is the third step of the CAC?
Go from Isocitrate to Alpha-Ketoglutarate
What enzyme is responsible for converting isocitrate to Alpha-ketoglutarate?
Isocitrate dehydrogenase
What is a byproduct when you go from isocitrate to Alpha-ketogluatarate?
CO2
NADH
What is the fourth step of the CAC?
Go from Alpha-keotglutarate to succinyl-CoA
What is the enzyme responsible for converting alpha-ketoglutarate to succinyl-CoA?
Alpha-ketoglutarate dehydrogenase complex
What is a byproduct when you go from alpha-ketoglutarate to succinyl-CoA?
CO2
NADH
What is the fifth step of the CAC?
Go from Succinyl-CoA to Succinate
What enzyme is responsible for converting succinyl-CoA to succinate?
Succinyl-CoA synthetase
What is a byproduct when going from succinyl-CoA to succinate?
ATP (GTP)
What is the sixth step of the CAC?
Go from Succinate to Fumarate?
What is the enzyme responsible for converting succinate to fumarate?
Succinate Dehydrogenase