Neisseria Flashcards
Habitat of N. Meningitidis and N. Gonorrhea
N. Meningitidis - Nasopharynx
N. Gonorrhea - Genitals
Disease caused by N. Meningitidis and N. Gonorrhea
N. Meningitidis - Meningitis
N. Gonorrhea - Gonorrhea
Shape of Neisseria Gonorrhea and Meningitidis
Gonorrhea - Kidney shaped
Meningitidis - Lens shaped
N Meningitidis and Gonorrhea are Catalase
Positive
N Meningitidis and Gonorrhea are Oxidase
Positive
Virulence factor of N. Meningitidis
Capsular Polysaccharide A,B,C,Y,W135
Outer membrane proteins of N. gonorrhea
Protein 1 - PORB1a - Disseminated infection, PORB1b - Localized
Protein ii
Transport media of N. Meningitidis and Gonorrhea
Amie’s Media
Stuart Media - Charcoal based
Selective media of N. Meningitidis and Gonorrhea
Modified Thayer Martin
Thayer Martin constituents
V - Vancomycin
C - Colistin
N - Nystatin
If Trimethoprim added - Modified Thayer Martin
Clinical features associated with Neisseria Meningitidis
Pyogenic meningitis (Fever, neck rigidity+ purpuric rash)
Bilateral adrenal hemorrhage (Waterhouse friedrichsen syndrome)
Chronic meningicoccemia
Post meningococcal Arthritis
Specimen taken for N. Meningitidis diagnosis
CSF
Nasopharyngeal swab
Which Strains of N. Meningitidis is protected by vaccine
A,C,Y,W135(Not B)
Whom to give Vaccine against N. Meningitidis
HHAAAT
Hypogammaglobunemia
HIV
Africa
Age
Asplenia
Terminal complement deficiency (MAC)
Treatment of N. Meningitidis
Iv Ceftriaxone
If allergic - Chloramphenicol