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Microbiology > Coccidian Parasites > Flashcards

Coccidian Parasites Flashcards

1
Q

Coccidian Parasites includes

A

Toxoplasma gondii
Isospora
Cryptosporidium
Cyclospora
Sarcocystis

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2
Q

Definitive and intermediate host in case of Toxoplasma gondii

A

Definitive - Cats (oocyst/Sexual reproduction)
Intermediate - Humans

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3
Q

Infective forms in case of Toxoplasma gondii infection

A

Sporulated oocyst
Tachyzoites
Bradyzoites

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4
Q

Mode of Transmission in case of Toxoplasma gondii

A

1) Ingestion - Sporulated cyst via contaminated food/water, Bradyzoites via contaminated undercooked meat
2) Blood transfusion - Tachyzoites (actively multiplying)

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5
Q

Congenital Toxoplasmosis is more severe in which trimester

A

1st trimester

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6
Q

Congenital Toxoplasmosis is more commonly transmitted in which trimester

A

3rd Trimester

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7
Q

Congenital Toxoplasmosis Clinical features

A

3C2M
Chorioretinitis
Cerebral calcification - Parenchymal
Convulsions
Microcephaly, Hydrocephalus
Mental retardation

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8
Q

Adult Toxoplasmosis C/F in immunocompetent pt.

A

Mostly asymptomatic
Painless Cervical Lymphadenopathy

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9
Q

Adult Toxoplasmosis C/F in Immunocompromised pt - HIV +ve

A

Encephalitis
M/C brain stem involvement

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10
Q

Adult Toxoplasmosis C/F in case of Bone marrow transplantation

A

Features of pneumonia
On CXR - Bilateral ground glass opacities

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11
Q

IgM + and IgG - Interpretation in case of Toxoplasmosis

A

Acute infection

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12
Q

IgM + , IgG + (low avidity) interpretation in case of Toxoplasmosis

A

Acute infection

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13
Q

IgM +, IgG + (Strong avidity) interpretation in case of Toxoplasmosis

A

Chronic infection

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14
Q

IgM -, IgG + interpretation in case of Toxoplasmosis

A

Remote infection

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15
Q

IgM -, IgG - interpretation in case of Toxoplasmosis

A

No infection

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16
Q

Toxoplasma gondi can be grown on

A

Intraperitoneal injection (mice) can grow
Non cultivable on cell free media

17
Q

Gold standard method in case of Toxoplasmosis infection

A

Sabin Feldman test - type of Complement fixation test

18
Q

Sabin Feldman test procedure

A

Patient serum (Ab +) + Tachyzoites - Activates complement system + add methylene blue - Tachyzoites distorted

If Ab + Colorless
If Ab - Color present

19
Q

Treatment of Toxoplasmosis

A

Pyrimethamine (+ Folinic acid) + Sulfadizine

20
Q

Organisms causing diarrhea in immunocompromised hosts

A

Cryptosporidium
Isospora
Cyclospora

21
Q

Which Coccidian parasites can cause autoinfection

A

Cryptosporidium

22
Q

Infective form in Cryptosporidium infection

A

Sporulated oocysts

23
Q

Sporozoites in case of Cryptosporidium attaches to

A

Brush border epithelium (Parasito-phorous vacuoles)

24
Q

Difference in life cycle of Cryptosporidium and Isospora, Cyclospora

A

In case of Isospora and Cyclospora
- No parasito phorous vacuoles
- released unsporulated oocyst (No autoinfection)

25
Q

Cyclospora is associated with consumption of

A

Raspberry

26
Q

Morphology of Cryptosporidium

A

4 sporozoites

27
Q

Morphology of Cyclospora

A

4 sporozoites (2 front and 2 back)
Like cycle - Cycle pr raspberry lene gye

28
Q

Isospora morphology

A

8 Sporozoites (4 in front and 4 in back)

29
Q

Size of Cryptosporidium, Cyclospora and Isospora

A

Cryptosporidium - 4 to 6 micron
Cyclospora - 8 to 12 micron
Isospora - 24 to 36 micron

30
Q

Shape of Cryptosporidium, Cyclospora and Isospora

A

Cryptosporidium and Cyclospora - Round
Isospora - Oval

31
Q

Stain used for Coccidian parasites

A

Acid fast (Cold Zn stain) or Kinyoun stain

32
Q

Which Coccidian parasites shows Immunofluorescence

A

Cyclospora and Isospora

33
Q

Treatment of Cryptosporidium, Cyclospora and Isospora

A

Cryptosporidium - Nitazoxanide
Cyclospora and Isospora - Cotrimoxazole

Microbiology (37 decks)

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