Hemoglobinopatia E Flashcards

1
Q

Hemoglobinopatia E - Epidemiologia

A

Prevalência → Sudeste Asiático

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2
Q

Hemoglobinopatia E - Origem

A

Alteração no gene que codifica β globina → na posição 26 da cadeia β (Ácido Glutâmico → Lisina)

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3
Q

Hemoglobinopatia E - Possibilidades 4

A

Heterozigoto → HbA/E

Heterozigoto → HbE/β+

Homozigoto → HbE/E

Heterozigoto → HbE/S

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4
Q

Heterozigoto → HbA/E = ?

A

Heterozigoto → HbA/E = Semelhante β-Talassemia Minor

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5
Q

Heterozigoto → HbE/β+ = ?

A

Heterozigoto → HbE/β+ = β-Talassemia Intermediária

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6
Q

Homozigoto → HbE/E = ?

A

Homozigoto → HbE/E = Anemia Branda

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7
Q

Heterozigoto → HbE/S = ?

A

Heterozigoto → HbE/S = Doença Falciforme

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8
Q

HbAE - Hemograma 2

A

Hb nL / ↓

Morfologia → microcitose / He em Alvo

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9
Q

HbE/E - Hemograma 2

A

↓↓↓ VCM

Morfologia → microcitose significativa

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10
Q

Significado

↓↓↓ = ?

↓ = ?

A

Significado

↓↓↓ = Diminuição Acentuada

↓ = Ligeiramente Diminuída

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