General Biology Flashcards
Prokaryotes (Prenucleus)
Single cellular except Cyanobacteria
Prokaryotes Domain 1
Bacteria (Environmental cyanobacteria/blue-green algae and Medically relevant bacteria)
Prokaryotes Domain 2
Archaea (Extreme habitats: high salt conc, jet fuel, high temperature)
Prokaryotes Characteristics
Circular chromosome, Cell wall with peptidoglycan
Eukaryotes (True nucleus)
Fungi and Parasites; Single or Multicellular organisms
Eukaryotes Characteristics
Linear chromosome, Cell wall with NO peptidoglycan
Infectious Particles
Viruses - Host-dependent infectious agents
Infectious Particles
Prions – Abnormal infectious proteins
TAXA
Domain – Kingdom – Phylum – Class – Order – Family – Genus – Species
Microbial Nomenclature
Binomial system; Latin/Greek-derived; Italicized or Underlined
Genus
First letter in UPPERCASE
Species
First letter in lowercase
Classification, nomenclature, and identification of organisms
Taxonomy
Variations in gene expression not caused by nucleic acid sequence similarities or differences
Epigenetics
Organizing microorganisms into groups based on similar traits
Classification
Methods providing microbiologists with relevant clinical information about a microorganism
Identification
Naming microorganisms according to ICNP rules
Nomenclature
Same species with same genetic make-up but with differential physiologic characteristics
Biotype/Biovar
A strain differentiated based on antigen types using specific antibodies
Serotype/Serovar
Specific version or subtype of an organism with minor differences
Strain
Characterization of etiologic agents using molecular techniques during an outbreak
Strain Typing/Sequencing
Macroscopic and microscopic morphology, staining characteristics, environmental & nutritional requirements, resistance profiles, antigenic & subcellular properties, chemotaxonomic properties
Phenotypic
DNA base composition ratio, nucleic acid base sequence, average nucleotide identity (ANI), genome-to-genome distance
Genotypic
Ability of a microorganism to produce disease in a host
Pathogenicity
Degree of damage caused by a microorganism to the host; degree of pathogenicity
Virulence
Growth of microorganisms that result in damage to host
Infection
Ingestion of preformed bacterial toxins present in food
Intoxication
Infection transmitted by direct contact between reservoir and host
Direct Transmission
Infection transmitted to host via intervening agents (vectors or vehicles)
Indirect Transmission
Results when infection produces notable changes in human physiology associated with damage or loss of function in one or more organ systems
Disease
Result of regular interaction with animals for food production
Livestock-associated Infection
Larger than normal number of diseased or infected individuals over a short period
Outbreak
Epidemiologic investigation involving data collection to characterize circumstances surrounding disease or infection
Surveillance
Father of microbiology; 1st microbiologist, 1st to describe bacteria
Antonie van Leeuwenhoek
Phenol as antimicrobial
Joseph Lister
Father of Epidemiology
John Snow
Proposed heat in killing bacteria (aseptic technique) and pasteurization
Louis Pasteur
Father of Taxonomy
Carl von Linne
Germ theory; Anthrax & Tuberculosis
Robert Koch
Father of Handwashing/Hospital hygiene; 80% decline in nosocomial infections
Ignaz Semmelweis
Endospore survival on boiling
Ferdinand Cohn
Father of virology; discovery of virus; use of enrichment and selective media
Martinus Beijerinck
Theory of chemolithotrophs; use of enrichment and selective media
Sergei Winogradsky
Discovered HIV that causes AIDS
Luc Montagnier
Developed >40 vaccines: against Hepatitis A and B, Measles, Mumps, Rubella, S. meningitidis, S. pneumoniae
Maurice Hilleman
Developed Gram stain technique
Hans Christian Gram
Inventor of PCR
Karry Mullis
Developed petri dish
Julius Richard Petri
Use of agar culture media instead of gelatin
Fanny Hesse