CHILDHOOD OBESITY Flashcards
CAN BEIGE ADIPOSE TISSUE PLAY A ROLE IN NON SHIVERING THERMOGENESIS AND WHY?
YES, BECAUSE IT EXPRESSES UCP1
BROWNING OF WHITE ADIPOSE TISSUE INTO BEIGE ADIPOSE TISSUE IS A PROCESS THAT COULD BE USEFUL IN MANAGEMENT OF WHICH CONDITION?
OBESITY
WHERE CAN BROWN ADIPOSE TISSUE BE FOUND IN ADULTS?
SCAPULAR AND PARAVERTEBRAL REGIONS
WHICH BMI SIGNIFIES MORBID OBESITY?
> 40
% OF OBESE AND OVERWEIGHT CHILDREN IN THE UK AGES 2-15?
28% (MORE THAN 1/4)
HOW MANY CHILDREN UNDER THE AGE OF 5 WERE OVERWEIGHT OR OBESE WORLDWIDE IN 2020?
39 MIL
WHAT IS CONSIDERED OBESE AND WHAT IS CONSIDERED OVERWEIGHT FOR CHILDREN UNDER 5?
OVERWEIGHT: BMI-FOR-AGE GREATER THAN 1 STANDARD DEVIATION ABOVE THE WHO GROWTH REFERENCE MEDIAN
OBESITY: BMI-FOR-AGE GREATER THAN 2 STANDARD DEVIATIONS ABOVE THE WHO GROWTH REFERENCE MEDIAN
WHAT IS MONOGENIC OBESITY?
RARE AND SEVERE EARLY ONSET OBESITY ASSOCIATED WITH ENDOCRINE DISORDERS (HIGH IMPACT OF GENETICS, ENVIRONMENT HAS LITTLE INFLUENCE)
MONOGENIC OBESITY IS MAINLY RELATED TO GENES ASSOCIATED WITH WHICH HORMONES?
LEPTIN AND MELANOCORTIN
WHAT IS SYNDROMIC OBESITY?
SEVERE OBESITY ASSOCIATED WITH ADDITIONAL PHENOTYPES SUCH AS MENTAL RETARDATION, DYSMORPHIC FEATURES, AND ORGAN SPECIFIC DEVELOPMENTAL ABNORMALITIES
HOW MANY SYNDROMES ASSOCIATED WITH SYNDROMIC OBESITY HAVE BEEN IDENTIFIED?
AROUND 100
% OF CHILDREN WITH BARDET-BIEDL SYNDROME WHO DEVELOP OBESITY?
80%
GENETIC CAUSES ACCOUNT FOR WHAT PERCENTAGE OF CHILDHOOD OBESITY?
5%
AFTER EXCLUDING GENETIC FACTORS, THE RISK FACTORS FOR CHILDHOOD OBESITY CAN BE DIVIDED INTO WHICH CATEGORIES?
- MATERNAL HEALTH DURING PREGNANCY/ IN UTERO EXPOSURE (EPIGEN. COMPONENT)
- PARENTAL HEALTH AND FAMILY SITUATION
- DIETARY HABITS
- PHYSICAL ACTIVITY
