Chapter 2.4 nucleic acids Flashcards
Nucleotides
Organic Compound with:
1.  nitrogenous base
2.  monosaccharide
3. One or more phosphate groups
Nitrogenous base
A single or double carbon – nitrogen ring
ATP structure
1.Adenine nitrogenous base
2. Ribose sugar
3. Three phosphate groups
Organization of ATP structural components in the molecule
Second and third phosphate groups of ATP attached by high energy covalent bonds because They are negative and repel each other. most energy transfers to and from ATP involve adding or removing the third phosphate
Function of ATP
physiological work such as Polymerization reactions, muscle contraction, pumping ions through cell membranes
Adenosine triphosphataces (ATPaces)
Enzymes that are specialized to hydrolyze the third phosphate bond in ATP to create ADP and Pi (in organic phosphate group)

ATP+H2O—ATPase—> ADP+Pi+Energy= heat and work
7.3 kcals of energy for every mole (505g) of ATP
Phosphorylation
“Switch” That turns metabolic pathways on or off
Or
Addition of Pi:
Free phosphate group released by ATP hydrolysis added to enzymes or molecules to activate them.
Why does life instantly cease without ATP?
ATP is short-lived and the entire amount in the body would support life for less than one minute if it weren’t continually replenished
Where in its molecular structure does ATP carry the energy that is transferred to other chemicals?
Third phosphate group.
Adenosine diphosphate (ADP)
Made after ATP releases third phosphate group (plus Pi)
Phosphorylation is carried out by what?
Enzymes called kinases
Glycolysis What is it, how much ATP produced?
First stage in glucose oxidation; sugar splitting. produces two ATP per glucose (The most of the energy is still in the pyruvate)
What happens to pyruvate depends upon what?
How much oxygen is available relative to ATP demand
Anaerobic fermentation
ATP demand > oxygen supply, Pyruvate—> lactate
-Temporary because lactate is toxic
-Enables glycolysis to continue