Chapter 2.4 nucleic acids Flashcards
Nucleotides
Organic Compound with:
1.  nitrogenous base
2.  monosaccharide
3. One or more phosphate groups
Nitrogenous base
A single or double carbon – nitrogen ring
ATP structure
1.Adenine nitrogenous base
2. Ribose sugar
3. Three phosphate groups
Organization of ATP structural components in the molecule
Second and third phosphate groups of ATP attached by high energy covalent bonds because They are negative and repel each other. most energy transfers to and from ATP involve adding or removing the third phosphate
Function of ATP
physiological work such as Polymerization reactions, muscle contraction, pumping ions through cell membranes
Adenosine triphosphataces (ATPaces)
Enzymes that are specialized to hydrolyze the third phosphate bond in ATP to create ADP and Pi (in organic phosphate group)

ATP+H2O—ATPase—> ADP+Pi+Energy= heat and work
7.3 kcals of energy for every mole (505g) of ATP
Phosphorylation
“Switch” That turns metabolic pathways on or off
Or
Addition of Pi:
Free phosphate group released by ATP hydrolysis added to enzymes or molecules to activate them.
Why does life instantly cease without ATP?
ATP is short-lived and the entire amount in the body would support life for less than one minute if it weren’t continually replenished
Where in its molecular structure does ATP carry the energy that is transferred to other chemicals?
Third phosphate group.
Adenosine diphosphate (ADP)
Made after ATP releases third phosphate group (plus Pi)
Phosphorylation is carried out by what?
Enzymes called kinases
Glycolysis What is it, how much ATP produced?
First stage in glucose oxidation; sugar splitting. produces two ATP per glucose (The most of the energy is still in the pyruvate)
What happens to pyruvate depends upon what?
How much oxygen is available relative to ATP demand
Anaerobic fermentation
ATP demand > oxygen supply, Pyruvate—> lactate
-Temporary because lactate is toxic
-Enables glycolysis to continue
Aerobic respiration
oxygen > ATP demand
-Breaks down pyruvate to carbon dioxide and water
-36 more molecules of ATP for each of the original glucose molecules
-Carried out in the mitochondria
Mitochondria
Cell’s principal ATP factory
Guanosine triphosphate
Nucleotide that can donate third Phosphate group to ADP to regenerate ATP
Cyclic adenosine monophosphate(cAMP)
Nucleotide formed by removal of both second and third phosphate groups from ATP. When the first messenger binds to a cell surface ATP converts to cAMP which acts as a second messenger to activate metabolic effects within the cell
Nucleic acids
Polymers of nucleotides
DNA (deoxyribonecleic acid)
-Largest nucleus acid: 1million to 1billion nucleotides long
- are genes, instructions for synthesizing proteins, transfers hereditary information from cell to cell when cells divide and from generation to generation when organisms reproduce
RNA (Ribonucleic acid)
Carries out DNA‘s instructions and synthesizes proteins