Ch 26 Aerobic respiration Flashcards

1
Q

What is the final electron acceptor in aerobic respiration

A

Oxygen; so electrons don’t run around as free radicals

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2
Q

Most of ATP is made where?

A

Mitochondria

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3
Q

Stages of cellular respiration

A
  1. Glycolysis (2ATP 2 NADH 2 Pyruvate)
  2. Pre-kreb’s prep cycle
  3. Krebs cycle
  4. Electron transport chain
  5. Chemiosmosis with ATP synthase
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4
Q

What happens in stage two: pre-Krebs cycle? And loses what via what?

A

-Pyruvate (3C) —>acetyl CoA (2C) via coenzyme A (loss of carbon atom by carbon dioxide)

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5
Q

Purpose of stage two pre-Krebs cycle?

A

-Preps carbon molecule for Krebs cycle
-passes pyruvate into mitochondrial matrix

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6
Q

End products of stage two pre-Krebs cycle?

A

2 NADH
2 CO2
2 acetyl CoA

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7
Q

What happens in stage three Krebs cycle or citric acid cycle?

A

Acetyl-CoA —> citric acid
 then cycle continues in the ring

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8
Q

Purpose of stage three Krebs cycle:

A

Use the Carbon to generate more NADH & FADH2 , Some CO2 byproduct

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9
Q

Net yield of stages 2and 3 of cellular respiration:

A

6 CO2
2 ATP
8 NADH
2 FADH2

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10
Q

How many times do mitochondrial matrix reactions occur?

A

Twice: because of 2 acetyl Co-A’s

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11
Q

What happens in Stage 4: electron transport chain

A

Electron carriers deliver electrons which move along protein complexes in inner membrane of mitochondria. Electrons picked up by oxygen which makes water.

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12
Q

Purpose of stage 4: electron transport chain

A

-Creates electron gradient: high H+ in inter-membrane
-regenerate NAD+ and FAD (Oxidize NADH and FADH2)

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13
Q

What happens in Stage five: Chemiosmosis?

A

Protons move down electrochemical gradient across membrane at ATP synthase pump which creates ATP

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14
Q

ATP synthase pump requires how many H+ for each ATP?

A

Requires 3H+ for each ATP

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15
Q

NAD+ releases at which enzyme complex? How many ATP are generated by NADH?

A

Complex 1; 2.5 ATP

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16
Q

FAD releases at which enzyme complex? How many ATP generated by FADH?

A

Enzyme complex 2and 3; FADH= 1.5 ATP

17
Q

How much ATP can you produce with FADH AND NADH?

A

2 FADH = 3 ATP
10 NADH = 25 ATP

18
Q

Stage at four and five generate how much ATP And regenerate what?

A

-28 HTP: 3 from FADH2, 25 from NADH
-Generates electron transporters: 10 NAD+, 2 FAD

19
Q

Total amount of ATP generated with cellular respiration (including glycolysis):

A

About 32 total ATP

20
Q

What metabolic poisons can disrupt ATP production?

A

Cyanide
Uncouplers

21
Q

How does cyanide disrupt ATP production?

A

Blocks parts of electron transport chain; prevents picking up of electrons and oxygen delivery so can’t create ATP= cell death

22
Q

How do on couplers disrupt ATP production?

A

Disrupt oxidative phosphorylation; pokes holes in mitochondrial membrane which lets protons Go across the gradient without using ATP synthase =less ATP = cell death

23
Q

What happens to pyruvate in aerobic respiration?

A

Pyruvate is oxidized to CO2 and H2O