blood clotting Flashcards
what are the different stages of blood clotting
- thrombokinase
- prothrombin
- thrombin
- fibrinogen
- fibrin
- blood cells trapped in the mesh
- scabs
describe thrombokinase
it is released from the ruptured platelets when they are exposed to air
describe prothrombin
the thrombokinase enzyme attaches to the prothrombin protein (substrate) which forms a second enzyme
describe thrombin
is the enzyme (product) formed from the reaction between the thrombokinase enzyme and prothrombin protein
describe fibrinogen
the thrombin enzyme connects to the fibrinogen
describe fibrin
fibrin is the insoluble product formed from the thrombin and fibrinogen reaction
describe blood cells trapped in the mesh
fibrin threads form a mesh that traps blood cells, platelets and plasma. this mesh with its trapped material is the clot to thrombus
describe scabs
a protective layer that covers the wound to allow a new layer of skin to form
what happens when minor damage does to a blood vessel
- arteries contract to reduce blood flow
- platelets stick to rough surfaces and attach more platelets, acting as a plug
- platelets release vasoconstrictor
- plug and concentration is enough to stop bleeding
what happens when major damage does to a blood vessel
- platelet plug is not enough to stop bleeding
- clotting factors present in plasma from fibrin
- fibrin forms a mesh
- mesh threads contract and bring sedges of blood vessels closer together
- serum is squeezed out forming a scab
what is a blood transfusion
- given to a person who has suffered excessive blood loss
- blood or blood product injected directly into the patient’s bloodstream