Adrenal dysfunction Flashcards
Addison’s disease
dysfunction in feedback loop, decreasing steroid production
Risk factors for addison’s disease that is not an autoimmune cause
TB, histoplasmosis
Treatment of addison’s disease
corticosteroids
s/s
increase in potassium retention, extracellular fluid deficiency (decreasing CO), loss of glucocorticoids, hypoglycemia, muscle weakness, lethargy, anorexia, weight loss, N/V, hyperpigmentation of skin and mucous membranes
Why does hormone replacement therapy need to be adjusted in times of stress and illness
there will be an increased demand on the adrenal glands, making the problem worse
How are exogenous glucocorticoids/corticosteroids taken
as prescribed, with antacids or meals
Types of exogenous glucocorticoids/corticosteroids
prednisone, hydrocortisone
goal of inpatient treatment
increase activity tolerance, keep stress low
What is important to Addison’s treatment
restoring fluid balance
How to restore fluid balance
increase sodium intake and avoid hot weather