47. Endocrine dermatopathies in dogs and cats Flashcards
sex hormone dependent dermatoses
sertoli cell tumour
hyperadrogenismus in male dogs
testosterone responsive alopecia
castration - responsive dematosis
hyperoestrogenism in females
oesstrogen - responsive dermatosis
hypogonadism in intact females
alopecia x
predisposition to sertoli cell tumour
boxer
shetland
poodle
pekingese
collie
mini schnauzer
any breed suffering from cryptochism
pathogenesis of sertoli cell tumour
excessive secretion of oestrogen
clinical signs of sertoli cell tumour
preputial swelling
hyperpigmentation
lichenification
feminisation
gynecomastia
dermatosis
alopecia
decreased libido
attracted to otehr males
BM depression
treatment of sertoli cell tumour
castration
another name for hyperadrogenismus in male dogs
leydig cell tumour
predisposition to leydig cell tumour
all breeds
middle/ old aged
clinical signs of leydig cell tumour
circumanal gland hyperplasia
tail gland hyperplasia
severe seborrhea oleosa
prostatitis
perianal adenoma
alopecia
treatment of leydig cell tumour
castration
predispositon to testosterone responsive alopecia
castrated males
clinical signs of testosterone responsive alopecia
symmetrical alopecia
dry hair
dull hair
lighter hair (initially)
seborrhoea
thin skin
hypotonic skin
scaling
treatment of testosterone responsive alopecia
methyltestosterone
predisposition of castration- responsive dermatosis
intact dogs
pomeranian
chow chow
malamute
huskey
clinical signs of castration- responsive dermatosis
fine, fluffy coat
symmetrical alopecia
hyperpigmentation
treatment of castration- responsive dermatosis
castration
predisposition to hyperoestrogenism in females
middle/ old aged bitches
aetiology of hyperoestrogenism in females
cystic ovaries / tumours
clinical signs of hyperoestrogenism in females
symmetrical alopecia
generalised alopecia
abnormal oestrus cycle
enlarged nipples
seborrhoea
lichenification
enlarged vulva
treatment of hyperoestrogenism in females
ovariohysterectomy
symptomatic treatment for seborrhea
predisposition to oestrogen responsive dermatosis
spayed females before first oestrus
clinical signs of oestrogen responsive dermatosis
symmetrical perianal alopecia
soft genital region
small nipples
puppy - like coat
small vulva
treatment of oestrogen responsive dermatosis
none
diethyl stilbestrol
hypogonadism in intact females cause
decreased functional activity of gonads
predisposition of hypogonadism in intact females
poodle
terrier
dachshund
primary hypogonadism
infertility is treated early –> no time for skin lesions to develop
secondary hypogonadism
irregular cycle
anoestrus
non cyclic alopecia
<3yrs old
slow progression
cyclic alopecia
starts with oestrus -> recovery -> may not recover in time before oestrus
to diagnose hypogonadism in intact females
exclude hypothyroidism and cushings
treatment of hypogonadism in intact females
spaying
other names for alopecia x
Hyposomatotropism
Sex hormone-responsive dermatosis
Castration-responsive dermatosis
Pseudo-Cushing’s
predisposition to alopecia x
young adults
all males
spayed females
poodles
localisation of alopecia x
everywhere except for head and paws
clinical signs of alopecia x
hyperpigmentation
broken hair shafts
alopecia
scaling skin
dry skin
thin skind
diagnosis of alopecia x
acth stimulation test
measure sex hormones
treatment of alopecia x
castration/ spay
melatonin
trilostan
mitotan
testosterone
