44. Allergodermatitis (without atopy) Flashcards

1
Q

History & signalment of dermatological exam

A

exercise intolerance
repro status
appetite
PU/ PD

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2
Q

Physical dermatological exam

A

systemic disease
dermatological problem

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3
Q

dermatological exam

A

localise and describe lesion
ectoparasites
characteristics of hair / skin

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4
Q

addictional diagnostic methods for dermatological exam

A

skin scraping
otoscope
biopsy
immunology tests

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5
Q

Aetiological classification of skin disease

A

congenital
bacterial
normergic dermatitis
autoimmune
ectoparasites
allergiv
fungal
neoplastic
endocrine
other

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6
Q

what is most important when treating allergodermatitis

A

to treat more than just the allergy

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7
Q

16 types of
Allergodermatitis

A

Atopic Dermatitis
Adverse food reaction
pruritus
allergy and hypersensitivity
immune mediated disorders
urticaria
angioedema
atopic like dermatitis
Flea bite hypersensitivity
contact dermatitis
feline psychogenic alopecia
feline miliary dermatitis
feline eosinophilic granuloma complex
autoimmune disroders
discoid lupus erythematosus
systemic lupus erythematosus

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8
Q

another name for Atopic Dermatitis

A

eczema

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9
Q

which allergodermatitis is most common

A

Atopic Dermatitis

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10
Q

what is Atopic Dermatitis characterised by

A

itchy
red
swollen & cracked skin

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11
Q

diagnosis of Atopic Dermatitis

A

exclusion

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12
Q

how common is Adverse food reaction

A

20% of cases

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13
Q

cause of Adverse food reaction

A

one or more proteins in food provokes allergies
type 1, 2, 4

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14
Q

Clinical signs of Adverse food reaction

A

gi signs
Dog - pruritus, seborrhea, urticaria
Cat - generalised pruritus, miliary dermatitis - like lesions, facial dermatitis, eosinophil plaque / granuloma

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15
Q

Diagnosis of Adverse food reaction

A

elimination trial
only give one protein at a time to figure out the cause of allergy
IgE testing

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16
Q

Treatment of Adverse food reaction

A

allergen avoidance
hypoallergenic diet

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17
Q

associated clinical signs of pruritus

A

alopecia
dermatitis
inflammation
hyperpigmentation
hot spot
redness
crusts
dandruff

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18
Q

Causes of pruritus

A

allergy
ectoparasite
infection
neoplasia
immune mediated
syringomyelia

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19
Q

diagnosis of pruritus

A

history - intensity, progression, diet, environment
physical exam - lesions, localisation, symmetry
skin scraping
blood test - sacoptes
elimination of contact dermatitis
elimination diet
allegy tests
skin biopsy

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20
Q

differential of pruritus

A

self mutilation
excessive licking
foreign body

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21
Q

treatment of pruritus

A

apoquel (oclacitinib)
cytopoint (lokivetmab)
cyclosporin

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22
Q

side effects of apoquel

A

skin nodule

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23
Q

side effect of cyclosporin

A

can be emetic
contrainficated in neoplasia and in cats with toxoplasma

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24
Q

allergy definition

A

hypersensitivity of immunological origin

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25
Q

atopy definition

A

predisposition to develop an allergic reaction

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26
Q

pseudoallergy definition

A

allergy which is non specific or non immunological

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27
Q

allergen definition

A

non infectious
non invasive
innocuous

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28
Q

immune mediated disorders

A

anaphylaxis
cytotoxic
immune complex
cell mediated

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29
Q

possible cause of anaphylaxis

A

urticaria
angiooedema
allergic dermatitis
atopy

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30
Q

possible causes of cytotoxic

A

pemphigus
drug
AIHA
foetal erythroblastosis

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31
Q

possible causes of immune complex

A

SLE
glomerulonephritis vasculitis
drugs

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32
Q

possible causes of cell mediated

A

allergic
autoimmune
catact allergen

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33
Q

urticaria

A

type I & III hypersensitivity reaction
acute onset

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34
Q

causes of urticaria

A

drugs
vaccine
insect bites

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35
Q

clinical signs of urticaria

A

localised / generalised wheals
hairs stand up over affected area
variable pruritus

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36
Q

treatment of urticaria

A

water soluble
gcc
antihistamines

37
Q

angioedema

A

type I hypersensitivity

38
Q

cause of angioedema

A

wasp and bee sting

39
Q

clinical signs of angioedema

A

extreme swelling of head, face and feet
laryngeal oedema

40
Q

treatment of angioedema

A

adrenaline
gcc
tracheotomy if necessary

41
Q

atopic like dermatitis

A

inflammatory & pruritic skin disease with similar clinical signs to atopic dermatitism
no IgE response to allergens

42
Q

Flea bite hypersensitivity

A

Flea Allergy Dermatitis - FADA
Type I & IV hypersensitivity

43
Q

Predisposed to FAD

A

dog > cat
seasonal

44
Q

FAD in dogs

A

usually presents as papular dermatitis on flank, ventral abdomen or caudal body
may produce - lichenification, acral lick granuloma, pyotraumatic dermatitis, seborrhea, alopecia, crusting
secondary infections with yeast and bacteria

45
Q

FAD in cats

A

miliary dermatitis
symmetrical alopecia
excoriations
eosinophilic granuloma complex

intense and constant pruritis

46
Q

Diagnosis of FAD

A

flea dirt
therapeutic trial

47
Q

Treatment of FAD

A

educate the owner
treat pruritis
prevent secondary infections
topical antiinflammatories
gcc - pred

48
Q

predisposition to contact dermatitis

A

any age
some genetic disposition
dogs with weakened immune status

49
Q

forms of contact dermatitis

A

allergic - contact dermatitis, immune system over reacts
irritant - contact dermatitis, direct damage to skin

50
Q

contact hypersensitivity

A

rare delayed type IV hypersensitivity

51
Q

cause of contact hypersensitivity

A

soap
pollen
disinfectant
shampoo
rubber
plastic

52
Q

clinical signs of contact hypersensitivity

A

erythema
macules
disinfectant
hyperpigmentation
pruritis

53
Q

diagnosis of contact hypersensitivity

A

scratch / patch testing

54
Q

primary irritant contact dermatitis

A

must be differentiated from contact hypersensitivity

55
Q

cause of primary irritant contact dermatitis

A

acids
alkalis
detergents
soaps
solvents

56
Q

Clinical signs of primary irritant contact dermatitis

A

localisation where hair is sparse
red rash
pruritis

57
Q

treatment of primary irritant contact dermatitis

A

bathing
topical gcc ointment

58
Q

feline psychogenic alopecia

A

caused by anxiety neurosis
excessive licking & grooming

59
Q

clinical signs of feline psychogenic alopecia

A

excessive licking & grooming
increased anxiety, nervousness
alopecia with no underlying inflammation
hairs at the affected site are broken

60
Q

treatment of feline psychogenic alopecia

A

environmental enrichment
phermone products
clomipramine
fluoxetine

61
Q

forms of feline eosinophilic granuloma complex

A

indolent ulcer
eosinophilic plaque
eosinophilic granuloma

62
Q

indolent ulcer form of feline eosinophilic granuloma complex

A

raised border
swelling

63
Q

eosinophilic plaque form of feline eosinophilic granuloma complex

A

demarcated
flat swellings of skin
reddened appearance
alopecia
pruritis

64
Q

eosinophilic granuloma form of feline eosinophilic granuloma complex

A

nodular / linear area of raised, thickened skin, hair - loss
ulceration
pruritis

65
Q

cause of feline eosinophilic granuloma complex

A

hypersensitivity reaction

66
Q

treatment of feline eosinophilic granuloma complex

A

systemic gcc
megestrol acetate

67
Q

causes of feline milary dermatitis

A

flea bite hypersensitivity
FAD
atopy
drug hypersensitivity
parasites
essential FA deficiency

68
Q

clinical signs of feline milary dermatitis

A

mild popular reaction
pruritus
self trauma from lickinf
increased hairball vomitting

69
Q

autoimmune disorders

A

pemphigus complex
pemphigus foliaceus
pemphigus vulgaris
pemphigus erythematous
pemphigus vegetans
bullous pemphigoid

70
Q

pemphigus complex

A

vesiculobullous ulcerative disorders of the skin and mucosa
autoantibody directed against epidermal intercellular cement

71
Q

pemphigus foliaceus

A

most common
clinical signs – vesiculobullous / exfoliative pustular dermatitis
hyperkeratosis of foot pads

72
Q

diagnosis of pemphigus foliaceus

A

IF

73
Q

pemphigus vulgaris

A

most severe
clinical signs - vesiculobullous lesions, ulcerative, erosive lesions, anorexia, depression, fever

74
Q

discoid lupus erythematosus

A

nasal solar dermatitis / collie nose dermatitis

75
Q

predisposed to discoid lupus erythematosus

A

collie
g. shepherd
shetland
sheepdog
huskey

76
Q

how is discoid lupus erythematosus exacerabated

A

by sunlight

77
Q

clinical signs of discoid lupus erythematosus
in dogs

A

erythema
alopecia
ulceration
loss of skin pigmentation
crsuting
scabbing
exudation

78
Q

clinical signs of discoid lupus erythematosus
in cats

A

self excoriation
skin peeling
crusting
erythema

79
Q

treatment of discoid lupus erythematosus

A

avoid sunlight
topical gcc
po pred
vit e
PABA containing suncream

80
Q

predisposed to systemic lupus erythematosus

A

collie
shetland sheepdog
g. shepherd
autoantibodies against many tissues

81
Q

how is systemic lupus erythematosus exacerbated

A

sunlight

82
Q

clinical signs of systemic lupus erythematosus are differentiated into

A

non cutaneous
cutaneous

83
Q

non cutaneous signs of systemic lupus erythematosus

A

polyarthritis
glomerulonephritis
lymphadenopathy
polymyositis
pyrexia
anaemia
pleuritis
pericarditis

84
Q

cutaneous signs of systemic lupus erythematosus

A

mucocutaneous ulcers
seborrhea
footpad lesions
alopecia
pyoderma

85
Q

diagnosis of systemic lupus erythematosus

A

IF of cutaneous lesions (major)
coombs positive (major)
thrombocytopaenia (major)
Fever, CNS signs, pleuritis (minor)
need 2 major and 1 minor

86
Q

treatment of systemic lupus erythematosus

A

gcc
cytotoxic drugs

87
Q

other causes of allergodermatitis

A

drug eruption
intestinal parasititic hypersensitivity
cold agglutinin disease
burns
frost bite
protein deficiency
essential FA deficiency
vitamin imbalances - A, biotin, nacin
zinc responsive dermatosis

88
Q
A