ZOONOSES Flashcards
Primarily affects GOATS, CATTLE,PIGS, DOGS
direct contact w/contaminated livestock or aborted PLACENTA
ingestion of infected/contaminate/unpasteurized dairy products
awrolization in lab or d.t. bioterrorism
Brucella spp
Sugar found in animal placentas (gusto ni Brucella)
ERYTHRITOL
Characteristic fever of BRUCELLOSIS
UNDULATING FEVER - peaks in the evening and returns to normal by morning
Vector of Francisella tularensis
TICK
Primarily a zoonotic disease and transmitted to human by BITING ARTHROPODS, DIRECT CONTACT W/INFECTED ANIMAL TISSUE, INHALATION OF AEROSOLS or INGESTION OF CONTAMINATED FOOD AND WATER
Tularemia
*fever, ulceration, swelling of LN, pneumonia
Tularemia subtypes
ULCEROGLANDULAR (from bite)
PNEUMONIA
OCULOGLANDULAR
TYPHOIDAL
Causative agent of PLAGUE
Spread to humans by FLEA BITE
Diagnosed by WAYSON’S STAIN (SAFETY PIN APPEARANCE)
Yersinia pestis
Vector of Yersinia pestis (black plague)
FLEA
Reservoir of Yersinia pestis
WILD RODENTS
Principal factors in the pathogenesis of plague
LIPOPOLYSACCHARIDE
ENDOTOXIN
COAGULASE
FIBRINOLYSIN
Major Virulent Factors of Yersinia pestis
Fraction 1 (F1) - capsular antigen that is ANTIPHAGOCYTIC
V and W antigens
Causative agent of Yersiniosis
Yersinia enterolitica
- ingestion of contaminated food or water
- unpasteurized milk
ingestion of contaminated food or water
from pigs din
Nausea, vomiting
diarrhea
abdominal pain (RLQ)
fever
mukhang APPENDICITIS
Yersiniosis
POST INFECTIOUS COMPLICATIONS
- erythema nodosum
- reactive arthritis
Regional lymph nodes (groin) swell and become red,hot,tender (bubo)
High fever
Conjunctivitis
Bubonic Plague
Bacteria survive in macrophages and spread to blood and organs
death occurs in 75% untreated
SEPTICEMIC PLAGUE