Intestinal Protozoa - ENTAMOEBA HISTOLYTICA Flashcards
Most invasive parasite among Entamoeba
Entamoeba histolytica
*eukaryotic organism that LACKS membrane bound organelles
Infective stage of E. histolytica
mature cysts
Found in DIARRHEAL STOOLS and within the INTESTINAL and EXTRAINTESTINAL lesions
TROPHOZOITE
Characteristically contain INGESTED RBCs (erythrophagocytosis) – HEMATOPHAGOUS
Trophoizoite
Predominates in NON-DIARRHEAL STOOLS
CYST
- smaller than E. coli
- has 4 nuclei
Mediates ADHERENCE
Lectin
For PENETRATION
Amebapores
For CYTOPATHIC EFFECT
Cysteine Proteases
Dysentery WITHOUT fever
FLASK SHAPED colon ulcer
Amebic colitis
granulomatous lesion that may form in the CECAL or RECROSIGMOID areas
associated w/ dysentery
AMEBOMA
MC EXTRAINTESTINAL FORM
usually in the POSTEROSUPERIOR ASPECT of the RIGHT lobe
ANCHOVY PASTE LIKE ASPIRATE
Amebic Liver Abscess
Treatment for Asymptomatic Cyst Carrier State
Diloxanide Furoate - DOC
Iodoquinol
Paromomycin
Treatment for Amebic Colitis
Metronidazole
Tinidazole
Diloxanide furoate
Paromomycin
Treatment for Amebic Liver Disease
Metronidazole
Tinidazole
Percutaneous drainage for nonresponders
TISSUE AMEBICIDES
act on organisms in the BOWEL WALL and LIVER
Chloroquine
Emetines
Metronidazole
Tinidazole