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Microbiology > Liver Trematodes (Flukes) - CLONORCHIS SINENSI > Flashcards

Liver Trematodes (Flukes) - CLONORCHIS SINENSI Flashcards

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Biology 101 flashcards
1
Q

Chinese Liver Fluke

A

Clonorchis sinensis

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2
Q

Intermediate Host of Clonorchis sinensis

A

SNAIL: Parafossarulus
FISH: Cyprinidae (Carp)

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3
Q

Ingestion of undercooked fish (freshwater - carp)

A

adult flukes live in the LIVER and CBD

CLONORCHIASIS
*inflammatory response can cause HYPERPLASIA and FIBROSIS OF RHE BILIARY TRACT

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4
Q

ACUTE DISEASE

A

fever, eosinophilia, lymphadenopathy, tender hepatomegaly

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5
Q

CHRONIC DISEASE

A

hepatibiliary disease
pancreatitis
CHOLANGIOCARCINOMA (Klatskin tumor)
neurocirculatory dystonia

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6
Q

Diagnostic test (Clonorchiasis)

A

Direct Fecal Smear

Potassium Permanganate Stain
*MELON LIKE RIDGES W/ ABOPERCULAR PROTUBERANCE

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7
Q

Treatment for Clonorchiasis

A

Praziquantel

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8
Q

(+) HBsAg
(+) IgM
(+) anti-HBc

A

ACUTE DIAGNOSIS

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9
Q

(+) HBsAg
(+) IgG
(+) anti-HBc

A

Chronic

(G)hronic

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10
Q

Markers of replication

A

HBeAg

HBV DNA

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11
Q

The only positive during WINDOW period

A

anti-HBc Igm

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12
Q

The only positive among VACCINATED patients

A

Anti-HBs

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13
Q

Differentiate CHRONIC ACTIVE infection from chronic carrier

A

HBeAg

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14
Q

Characterized by PERSISTENCE OF HBsAg for at least 6 mos

A

Chronic Infection

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15
Q

PRINCIPAL MARKER of risk for developing liver disease and liver cancer (HCC)

A

Persistence of HBsAg

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16
Q

The BEST PREDICTOR of CHRONICITY

A

AGE at the time of INFECTION

*the younger the age at the time of HBC infection the higher the probability of chronicity

17
Q

1sy vaccine to prevent human cancer

A

Hepatitis B vaccine

  • 1st dose - first 12 hrs of life
  • subsequent doses are given at least 4 weeks apart
  • 3rd dose - > 24 weeks of age
18
Q

Eosinophilic globule of cells that represents a DYING HEPATOCYTE often surrounded by NORMAL PARENCHYMA

A

Councilman Body

Microbiology (106 decks)

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