GRAM NEGATIVE RODS - GIT AND GUT Flashcards
lactose fermenter
GREEN sheen
Escherichia coli
lactose fermenter
UREASE (+)
ESBL
Klebsiella pneumoniae
comma-shaped
motile
OXIDASE (+)
Vibrio cholerae
comma-shaped
microaerophilic
SKIRROW’S AGAR
Campylobacter jejuni
comma-shaped
UREASE (+)
Helicobacter pylori
LACTOSE FERMENTERS
KEEC
Klebsiella
Escherichia coli
Enterobacter
Citrobacter
WATERY DIARRHEA
MONTEZUMA’s REVENGE
TRAVELLER’s DIARRHEA
EnteroToxigenic E. coli ( ETEC)
heat labile - inc cAMP
heat stable - inc cGMP
bloody diarrhea, mucus, fever
INVASIVE - hemorrhagic diarrhea but WITHOUT HUS
EnteroInvasive E. colo (EIEC)
rare
enterotoxin
hemorrhagic colitis hemolytic uremic syndrome (HUS) *microangiopathic hemolysis *uremia *thrombocytopenia
children, elderly
EnteroHemorrhagic E. coli (EHEC)/Shiga like toxin (STEC)
O157.H7
shiga like toxin/verotoxins
*(-) mammalian protein synthesis via 60s ribosomal subunit
transmitted via UNDERCOOKED MEAT (burgers etc.)
watery diarrhea of long duration
INFANTS
DEVELOPING COUNTRIES
EnteroPathogenic E. coli (EPEC)
pediatric, poverty, Pinas
persistent watery diarrhea in children and patients infected w/ HIV
EnteroAdherent E. coli (EAEC)
AIDS
MCC of community acquired UTI
2nd MCC of neonatal meningitis
Escherichia coli
For attachment, colonization factor, associated w/ UTI
E. coli
PILI OR FIMBRIAE
Associated w/ PNEUMONIA and NEONATAL meningitis
capsule (K)
27/M develops severe abdominal cramping and bloody diarrhea. Patient reports consuming rare hamburger days prior to the onset of the symptoms.
This best describes the toxin-mediated mechanism of this disease process
(-) of 60s ribosomal subunit – decreased protein synthesis in GI mucosal cells