MYCOBACTERIA

Question 1

Tiniest free living organisms capable of self replication

lacks peptidoglycan walll

Answer 1

Mycoplasma pneumonia

Question 2

Mycoplasma pneumonia

adheres to epithelial cells of respiratory tract

Answer 2

PROTEIN P1 ADHESIN

• toll like receptor 2 protein
• cause INHIBITION of ciliary motion (ciliostasis) and necrosis

Question 3

Mycoplasma pneumonia

contributes to the damage to the respiratory tract cells

Answer 3

Hydrogen Peroxide

Question 4

Mycoplasma pneumonia

major role in damage to the respiratory epithelium

Answer 4

COMMUNITY ACQUIRED RESPIRATORY DISEASE TOXIN (CARDS)

• exotoxin
• ADP-ribosylating and vacuolating cytotoxin similar to pertussin toxin

Question 5

MCC of ATYPICAL PNEUMONIA

Answer 5

Mycoplasma pneumonia

“WALKING PNEUMONIA”

CXR - patchy infiltrates

Question 6

EXTRAPULMONARY FINDINGS (Mycoplasma pneumonia)

Answer 6

STEVENS JOHNSON SYNDROME - MC infectiois cause is M. pneumoniae

Erythema multiforme

Hemolysis

Raynaud’s

Guillain Barre syndrome

Question 7

Culture used for Mycoplasma pneumonia

Answer 7

EATON AGENT

• requires cholesterol and nucleic acid
• add penicillin to (-) growth of contaminating bacteria
• DOME SHAPED COLONIES with FRIED EGG or MULLBERRY APPEARANCE