Blood and Tissue Protozoa - TOXOPLASMA GONDII

Question 1

Definitive host of Toxoplasma gondii

Answer 1

domestic CAT

Question 2

Transmission of Toxoplasma gondii

Answer 2

ingestion of cysts in raw meat, contaminated food

transplacentally

blood transfusion

Question 3

Infective stage of T. gondii

Answer 3

fecal OOCYSTS

Question 4

2 types of trophozoites

Answer 4

Tachyzoites

Bradyzoites

Question 5

RAPIDLY multiplying

cell mediated immunity usually limits the spread

seen in BODY FLUIDS in early acute infections

Answer 5

TACHYZOITES

Question 6

SLOWLY multiplying

contained in cysts in MUSCLE and BRAIN TISSUE and EYE

Answer 6

BRADYZOITES

Question 7

IMMUNOCOMPETENT

Answer 7

resembles INFECTIOUS MONONUCLEOSIS BUT (-) heterophil antibody test

Question 8

IMMUNOCOMPROMISED

Answer 8

encephalitis

brain abscess - MULTIPLE RING ENHANCING LESIONS

Question 9

can result in abortion, stillbirth, or neonatal disease w/ HYDROCEPHALUS, encephalitis, CHORIORETINITIS and hepatosplenomegaly

Answer 9

CONGENITAL TOXOPLASMOSIS

• fever, jaundice and INTRACRANIAL CALCIFICATIONS
• CMV - PERIVENTRICULAR calcifications

Question 10

Treatment for Toxoplasma gondii

Answer 10

Sulfadiazine + Pyrimethamine

allergic to sulfa drugs
*CLINDAMYCIN