Year One drug list Flashcards
what is a partial agonist at α4β2 nicotinic acetylcholine
receptors used to reduce craving for cigarettes and feelings of irritability.
Varenicline
what drugs can you use to treat asthma attacks
Salmeterol, salbutamol, pindolol
amlodipine
calcium channel blocker,
angina and hypertension
Bisoprolol
competitive inhib of B1
decreases heart contraction
atenolol
selective competitive antagonist of B1
Pindolol
partial agonist of B1 and B2
Propranolol
antagonist on B1,2,3
slows HR
NOT for asthmatics
metaprolol
antagonist B1 and B2
used for heart failure
carvedilol
antagonist at A1 - stops vasoconstriction
reduces BP
antagonist at B1 - slows HR
Sotalol
Potassium channel blocker
Salbutamol
agonist on B2
vasodilation
used for asthmatics
Asprin
NSAID
inhibs COX 1
activates platelets
decreases thromboxane
codeine
opiod receptor
reduces pain
lidocaine
topical anesthetic
block sodium voltage gated ion channels
paracetamol
breaks down to NAPQI (which isn’t great for you)
weak inhibitor of COX 1 and COX2
Sodium Valporate
increased GABA as GAB inhibs excitation in the brain
theophylline
phosphodiesterase inhibitor
Prevents conversion of cAMP to AMP, keeps cellular signalling action going
Amitriptyline
antagonist at M1-5 and NET and SERT
side effect - dry mouth and constipation
antidepressent
sertraline
(SSRI)
decrease reuptake of serotonin
warfarin
inhibits coagulation cascade - Factor 2,7,9,10
herapin
inhibits thrombin and F10a (FXa)
Omeprazole
proton pump inhibitor
Which signalling molecules is secreted in response to hyponatremia and binds to nuclear
receptors in the cortical collecting duct?
Aldosterone
amitriptyline has side effects of dry mouth, constipation and dizziness due to»>
Antagonism at muscarinic acetylcholine receptors
what is the most cardio selective beta blocker
bisoprolol
what is the pKa of aaspirin
3.5
