Year One drug list

Question 1

what is a partial agonist at α4β2 nicotinic acetylcholine
receptors used to reduce craving for cigarettes and feelings of irritability.

Answer 1

Varenicline

Question 2

what drugs can you use to treat asthma attacks

Answer 2

Salmeterol, salbutamol, pindolol

Question 3

amlodipine

Answer 3

calcium channel blocker,
angina and hypertension

Question 4

Bisoprolol

Answer 4

competitive inhib of B1
decreases heart contraction

Question 5

atenolol

Answer 5

selective competitive antagonist of B1

Question 6

Pindolol

Answer 6

partial agonist of B1 and B2

Question 7

Propranolol

Answer 7

antagonist on B1,2,3
slows HR
NOT for asthmatics

Question 8

metaprolol

Answer 8

antagonist B1 and B2
used for heart failure

Question 9

carvedilol

Answer 9

antagonist at A1 - stops vasoconstriction
reduces BP
antagonist at B1 - slows HR

Question 10

Sotalol

Answer 10

Potassium channel blocker

Question 11

Salbutamol

Answer 11

agonist on B2
vasodilation
used for asthmatics

Question 12

Asprin

Answer 12

NSAID
inhibs COX 1
activates platelets
decreases thromboxane

Question 13

codeine

Answer 13

opiod receptor
reduces pain

Question 14

lidocaine

Answer 14

topical anesthetic
block sodium voltage gated ion channels

Question 15

paracetamol

Answer 15

breaks down to NAPQI (which isn’t great for you)
weak inhibitor of COX 1 and COX2

Question 16

Sodium Valporate

Answer 16

increased GABA as GAB inhibs excitation in the brain

Question 17

theophylline

Answer 17

phosphodiesterase inhibitor
Prevents conversion of cAMP to AMP, keeps cellular signalling action going

Question 18

Amitriptyline

Answer 18

antagonist at M1-5 and NET and SERT
side effect - dry mouth and constipation
antidepressent

Question 19

sertraline

Answer 19

(SSRI)
decrease reuptake of serotonin

Question 20

warfarin

Answer 20

inhibits coagulation cascade - Factor 2,7,9,10

Question 21

herapin

Answer 21

inhibits thrombin and F10a (FXa)

Question 22

Omeprazole

Answer 22

proton pump inhibitor

Question 23

Which signalling molecules is secreted in response to hyponatremia and binds to nuclear
receptors in the cortical collecting duct?

Answer 23

Aldosterone

Question 24

amitriptyline has side effects of dry mouth, constipation and dizziness due to»>

Answer 24

Antagonism at muscarinic acetylcholine receptors

Question 25

what is the most cardio selective beta blocker

Answer 25

bisoprolol

Question 26

what is the pKa of aaspirin

Answer 26

3.5