79. Physiology - Control of arterial blood pressure 1 Flashcards

1
Q

what is blood pressure

A

“the outwards (hydrostatic) pressure exerted by the blood on blood vessel walls”

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2
Q

what is ‘systemic systolic arterial blood pressure’

A

the pressure exerted by the blood on the walls of the aorta and systemic arteries when the heart contracts

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3
Q

systolic blood pressure should not reach/exceed what?

A

140 mm Hg

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4
Q

what is Diastolic Arterial Blood Pressure

A

the pressure exerted by the blood on the walls of the aorta and systemic arteries when the heart relaxes

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5
Q

diastolic blood pressure should not reach/exceed…?

A

90 mm Hg (under resting conditions)

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6
Q

what is the term for very high blood pressure

A

hypertension

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7
Q

define hypertension

A

Clinic blood pressure of 140/90 mmHg or higher and day time average of 135/85 mmHg or higher

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8
Q

what is pulse pressure

A

the difference between systolic and diastolic blood pressure

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9
Q

what is the pulse pressure is systolic BP is 120 and diastolic is 80

A

40 mm Hg

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10
Q

what is the normal rage for pulse pressure

A

30 and 50

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11
Q

can Laminar Flow in Normal Arteries be heard

A

no

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12
Q

If external pressure (e.g. cuff pressure) exceeding the systolic blood pressure is applied to an artery. What happens? Can you hear anything

A

The flow in that artery would be blocked and no sound is heard through a stethoscope

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13
Q

if the external pressure is kept between systolic and diastolic pressure the flow becomes…. and can you hear anything

A

turbulent. yes, you can hear.

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14
Q

what equipment is used for blood pressure

A

sphygmomanometer and stethoscope

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15
Q

when is diastolic pressure recorded

A

fifth Korotkoff sound (point when sound disappears)

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16
Q

when do you record systolic BP

A

1st Korotkoff sound (first appearance of sound)

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17
Q

a pressure gradient between ……and ….. …… drives blood around the systemic system

A

aorta and right atrium

18
Q

how would you calculate the pressure gradient

A

Mean Arterial Pressure (MAP) – Central Venous (right atrial) Pressure (CVP)

19
Q

what is mean arterial blood pressure (MAP)

A

the average arterial blood pressure during a single cardiac cycle, which involves contraction and relaxation of the heart

20
Q

how can MAP be estimated

A

MAP = (2x diastolic pressure) + systolic pressure
divided by 3

21
Q

so if systolic BP is 120 and diastolic BP is 80. what is MAP?

A

93.3 mmHg

22
Q

what is the normal range of MAP

A

70 -105 mmHg

23
Q

MAP of at least … mm Hg is needed to perfuse the coronary arteries, brain, and kidney

A

60

24
Q

what happens if MAP is to high

A

puts strain on vital organs

25
Q

what is cardiac output

A

The volume of blood pumped by each ventricle of the heart per minute

26
Q

what is stroke volume

A

Stroke Volume is the volume of blood pumped by each ventricle of the heart per heart beat

27
Q

what is systemic vascular resistance

A

The sum of resistance of all vasculature in the systemic circulation

28
Q

which vessels are the major resistance vessels

A

arterioles

29
Q

what is the short term regulation of mean arterial blood pressure

A

the baroreceptor reflex

30
Q

what kind of feedback does baroreceptor reflex use

A

negative

31
Q

where are the baroreceptors

A

Carotid Baroreceptor - carotid artery- via IXth CN
Aortic Baroreceptors - aorta-via Xth CN

32
Q

where do baroreceptors signal

A

send signals through the Vagus and glossopharyngeal nervs to the medulla

33
Q

The baroreceptor reflex helps maintain stable blood pressure, especially during sudden changes like when?

A

Postural changes aka standign up quickly

34
Q

when you stand up quickly, what happens to your venous return and MAP

A
  • Gravity causes blood to pool in your legs which reduces venous return to the heart
  • MAP briefly drops
35
Q

when you stand up quickly, your MAP drops. what happens next?

A

the drop in MAP reduces the firing rate of baroreceptors

36
Q

what are the autonomic adjustments when you stand up quickly and decrease MAP.

A
  1. Decrease Vagal tone increasing HR and SV (Vagal tone refers to the activity of the vagus nerve, which is a key part of the parasympathetic nervous system)
  2. Increased sympathetic tone - sympathetic tone increases causing
    Inc. SVR (arterioles constrict)
    Inc Venous return (veins constrict)
37
Q

failure of Baroreceptor responses to gravitational shifts in blood, when moving from horizontal to vertical position is called?

A

Postural Hypertension

38
Q

risk factors of postural hypertension are…?

A

Age, medication, certain diseases, prolonged bed rest, reduced intravascular volume

39
Q

Baroreceptors ONLY Respond to ‘…………’ Changes in Blood Pressure

A

Acute

40
Q

baroreceptor firing decreases if HBP is …..?

A

sustained

41
Q

Control of MAP in the longer-term is mainly by control of…?

A

Blood Volume