94. Embryology Flashcards

1
Q

how many stages in embryology

A

23 Carnegie stages based on morphological characteristics

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2
Q

developmental periods are how long

A

9 months / 38-40 weeks / 3 trimesters

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3
Q

how long is conceptus embryo

A

0-3 weeks

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4
Q

embryonic period is how long

A

3-8 weeks

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5
Q

foetal period is how long

A

9-40 weeks

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6
Q

what is teratology

A

The study of abnormal development (terato=abnormal)

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7
Q

what are teratogens

A

Teratogen is an agent that the mother is exposed to that can cause abnormalities.

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8
Q

name the 5 types of teratogens

A
  1. physical
  2. chemical
  3. nutritional
  4. hormonal
  5. infection
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9
Q

when is teratogen risk highest

A

first 8 weeks - embryonic period

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10
Q

what kinds of things are types of teratology

A

deformation
malformation
disruption

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11
Q

describe malformation

A

Complete absence or partial absence of a structure or alterations in its normal configuration
Can be caused by environmental factors and/or genetic factors
E.g. poldactyl

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12
Q

describe Disruption

A

Morphological alterations of already formed structures and are caused by destructive processes
E.g. amniotic band syndrome

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13
Q

describe deformation

A

Abnormal form due to mechanical factors over a prolonged period
E.g. clubfoot (equinovarus foot)

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14
Q

Phases of Embryogenesis

A

Gametogenesis,
Fertilization
Cleavage
Gastrulation
Morphogenesis
Organogenesis

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15
Q

how many chromosomes in diploid cell

A

46

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16
Q

what is gametogenesis

A
  • formation of a gamete form a primordial cell
17
Q

what is a gamete

A

a cell like an ovum or sperm with a complement of 23 chromosomes aka half of a somatic cell

18
Q

gamete is haploid/diploid?

A

haploid

19
Q

what kind of division do haploid cells go through

A

Consisting of mitosis and meiosis

20
Q

what is the formation of male gametes called

A

spermatogenesis

21
Q

how long is the process of spermatogenesis and how much sperm is produced per day?
when does spermatogenesis begin and when does it end

A

64-74 days
300 million per day
Begins at puberty and continues throughout life

22
Q

name the 3 phases and order of spermatogenesis

A

Spermatogonial Phase
Spermatocyte Phase
Spermatid Phase

23
Q

what is the process called of the formation of female gametes

A

Oogenesis

24
Q

when does Oogenesis start and when does it end

A

starts - development
ends- menopause

25
Q

fertilisation is

A

the union of gametes/ fusion of spem and oocyte/
formation of zygote

26
Q

describe a zygote

A

diploid
single cell embryo
sex determination (46xx/46xy)

27
Q

cleavage is the period of

A

rapid mitotic cell division with no increase in size

28
Q

cleavage causes the formation of what then what

A

Morula (16+ cells) then Blastocyst

29
Q

End of second week a ….. is formed

A

bilaminar disc

30
Q

Start of third week there is…..

A

gastrulation (trilaminar)

31
Q

what is gastrulation

A

The process that establishes all three germ layers
Ectoderm
Mesoderm
Endoderm

32
Q

Body folding days

A

cranial and lateral - day 22
caudal - day 23

33
Q

what is the name for formation of organs and organ systems

A

organogenesis

34
Q

foetal period where most growth and weight gain is

A

Mainly grows in length during 2nd trimester

Most weight is added in 3rd trimester

35
Q

name the Primary Developmental Processes

A

Cell Division​
Increase in number of cells​
Influence shape and growth

Differentiation​
Change in appearance/structure​
Adoption of new functions​ (specialization)

Cell Attachment​
Physical/functional linkages​ between cells
Formation of tissues​

Apoptosis​
Programmed cell death​
Creates spaces and cavities

Induction
Ability of one cell type to cause another to differentiate
Directly or at a distance

Cell migration
Movement from one location to another

36
Q

Secondary Developmental Processes

A

Axis formation/ Polarity
- Cell will understand its position

Folding/ Rotation
- Entire embryo or structures within it

Increases /Decreases in mass or dimension
-Compaction
- Expansion: hypertrophy/hyperplasia