92. Atheroma and its complications Flashcards

1
Q

Name the 4 complications of atheroma

A

STENOSIS
ANEURYSM
DISSECTION
THROMBOSIS AND EMBOLISM

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2
Q

what is arterial stenosis

A

narrowing of the arterial lumen
reduced elasticity
reduced flow in systole

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3
Q

what can be the result from arterial stenosis

A

Tissue Ichaemia

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4
Q

which arteries are affected by arterial stenosis, give me examples

A

any. more common in branching areas with more turbulent blood flow
- coronary arteries
-carotid arteries (v common)
-renal arteries
-peripheral arteries (Ichaemia of lower limbs)

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5
Q

blockage of carotid arteries can lead to what

A

TIA, Stroke and Vascular dementia

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6
Q

what does aneurysm mean

A

weakening of the vessel wall
aka
abnormal and persistent dilation of an artery due to the weakness of its wall

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7
Q

most common site of aneurysm is

A

abdominal aorta

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8
Q

name the types of aneurysms

A

mycotic, atherosclerotic, dissecting, congenital, arteriovenous, traumatic, syphillic

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9
Q

complications of aneurysm

A

-rupture
-thrombosis
-embolism
- pressure erosion of adjacent structures
- infection

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10
Q

Complication of an aneurysm is a rupture. At what size does this start to be a concern

A

6cm or bigger

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11
Q

what is arterial dissection

A

splitting in the media by flowing blood

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12
Q

what age does dissection tend to occur at

A

middle aged

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13
Q

arterial dissection occurs - so split media by blood. What does this leave us with

A

a ‘false lumen’ which is filled with blood in the media

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14
Q

what does a dissection false lumen cause the patient to do

A

sudden collapse and high mortality

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15
Q

what is some strong associations with aortic dissection

A

atheroma
hypertension
trauma
coarctation
marfan’s
pregnancy

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16
Q

what is MARFAN’s syndrome

A

genetic disorder

17
Q

where is the MARFAN’s genetic disorder - what gene is it

A

fibrillin gene on Ch15

18
Q

what is coarctation

A

congenital disorder - so was present at birth and results in abnormal formation of aorta

19
Q

what can coarctation predispose

A

aneurysm formation

20
Q

describe what coarctation actually is

A

a section of the aorta is abnormally narrow

21
Q

what is the genetic disorder of the fibrillin gene on CH15

A

MARFAN’s syndrome

22
Q

what gene is affected with MARFAN’s syndrom

A

fibrillin gen on Ch15

23
Q

Trauma is caused usually by what

A

road traffic accidents (RTA)

24
Q

why does RTA (road traffic accidents) cause trauma and dissection

A

causes rapid deceleration and whiplash like injuries