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exam stuff > year 3 passssmeddd > Flashcards

year 3 passssmeddd Flashcards

1
Q

how do you give prophylaxis for tumour lysis syndrome

A

IV allopurinol or Iv rasburicase

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2
Q

what is found in cryoprecipitate

A

factor VIII, fibrinogen, von Willebrand factor and factor XIII

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3
Q

what type of anaemia does methotrexate therapy cause

A

can cause folate deficiency so therefore can cause
-megaloblastic macrocytic anaemia

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4
Q

which Hodgkin’s lymphoma carries the best prognosis

A

lymphocyte predominant

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5
Q

philadelphia chromosome, t(9:22)

A

CHRONIC MYELOID LEUKAEMIA

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6
Q

which anticoagulant for DVT

A

DOAC!!!!!!!!!!!!!!!
-apixaban or rivaroxaban

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7
Q

isolated rise in gamma GT in the context of macrocytic anaemia suggests that what is the cause?

A

alcohol excess

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8
Q

which is the most common type of haemophilia

A

A!!!!! !!! !
factor 8 deficiency

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9
Q

cancer patients with a VTE, what treatment

A

DOAC for 6 months

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10
Q

DVT investigation: if the scan is negative, but the D-dimer is positive?

A

stop anticoagulation and repeat scan in 1 week

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11
Q

where are vestibular schwannomas usually found

A

the cerebellopontine angle

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12
Q

at what level of the spinal cord does autonomic dysreflexia occur

A

above T6

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13
Q

can you give someone with poorly controlled epilepsy sertraline

A

no

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14
Q

second line treatment for OCD if SSRI contraindicated

A

clomipramine

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15
Q

how does controlled hyperventilation work to reduce ICP

A

reduces CO2 > vasoconstriction of cerebral arteries > reduced ICP

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16
Q

is the forehead spared in bell’s palsy

A

NOOOOO
-cannot raise eyebrows
-LMN lesion

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17
Q

triple test results for downs syndrome

A

increased HCG
decreased PAPP-A
thickened nuchal translucency

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18
Q

investigation for suspected miscarriage

A

TVUSS

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19
Q

when can medical management be used for an ectopic

A

1) An unruptured embryo
2) <35mm in size
3) Have no heartbeat
4) Be asymptomatic
5) Have a B-hCG level of <1,000IU/L and declining

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20
Q

can an SSRI be taken with warfarin

A

no
-increases risk of bleeding especially in elderly people

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21
Q

what is richter transformation

A

when CLL transforms into aggressive high grade B cell lymphoma

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22
Q

what does parovirus B19 infection cause

A

slapped cheek (aka erythema infectiosum)
-this can cause aplastic crisis in sickle cell

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23
Q

A swab reveals the presence of ballooned multinucleated giant cells and eosinophilic inclusion bodies.

A

herpes simplex 2

24
Q

when should warfarin be stopped and vitamin K administered

A

when the INR is over 8

25
Q

what medication for chemo induced nausea

A

odanestron

26
Q

which neurofibromatosis causes peripheral neurofibromas and axillary/groin freckles

A

1

27
Q

what nerve injury are mid humeral shaft fractures associated with

A

radial nerve

28
Q

what should you think when there is a mixture of LMN and UMN signs

A

MND

29
Q

what is the most common cause of brain mets

A

LUNG CANCER

30
Q

what is subdural haemorrhage caused by

A

damage to bridging veins between cortex and venous sinuses

31
Q

which contraception has the highest success rate

A

progesterone only implant

32
Q

if you miss one POP how long do you need to use barrier methods for

A

48 hours

33
Q

lynch syndrome increases ur risk of which repro cancer the most

A

endometrial the most
-then ovarian

34
Q

how do you assess fetal growth in obese women

A

USS

35
Q

if a woman who is pregnant has a BMI of 50 what do they need further encouragement to do

A

breastfeed
-obese women are less likely to breast feed

36
Q

which part of the MMR can cause obstructive infertility and reduce spermatogenesis

A

mumps

37
Q

when can pregnant women get a cervical smear

A

not until they are 3 months post partum

38
Q

how does a pituitary tumour decrease fertility in males

A

-decrease LH, FSH
-decreased testosterone

39
Q

how do hypothalamus disorders decrease fertility in males

A

-decrease LH, FSH
-decreased testosterone

40
Q

how does hyperthyroidism decrease fertility in males

A

decreased sexual function

41
Q

how does hypothyroidism decrease fertility in males

A

increased prolactin

42
Q

how does diabetes decrease fertility in males

A

decreased testosterone
decreased sexual function

43
Q

investigation for primary ovarian insufficiency (premature ovarian failure)

A

FSH levels x2

44
Q

what is gravida

A

the number of times a woman has been pregnant regardless of the gestation at delivery and includes current pregnancy

45
Q

what does parity mean

A

the number of potentially viable babies a woman has delivered; this includes all live births and still births delivered after 24 weeks. So, this is written as P2 and is followed by “+” which represents all the pregnancies up to 24 weeks that did not result in live births

(delivered 2 babies)

46
Q

which HRT increases risk of VTE

A

oral oestrogen only

47
Q

which HRT for someone with high risk of DVT

A

transdermal oestrogen patch
-also need to insert mirena IUS for the progesterone part

48
Q

which gynaecological malignancy is associated with gelatinous tumour in the peritoneal cavity

A

ovarian

49
Q

coffee bean nuclei and exner bodies

A

sex cord ovarian tumour

50
Q

where can the fundus be felt at 12 weeks

A

symphysis pubis

51
Q

active labour over how many hours puts u at risk of PPH

A

12

52
Q

which movement before expulsion

A

external rotation

53
Q

What antibodies are formed by the mother when first exposed to a red cell antigen?

A

IgM

54
Q

first line investigation for urinary incontinence

A

urine dipstick

55
Q

what is the nerve supply to the urethral smooth muscle

A

Sympathetic nerves derived from the spinal cord at T10 to L2, but descending to the bladder and urethra via the hypogastric nerves

56
Q

can pyroxidine be used for hyperemesis gravidarum

A

no

57
Q

name 4 things that causes a raise in CA125 levels

A

-endometriosis
-ovarian cancer
-pregnancy
-pancreatitis

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