year 3 passmed again Flashcards
DIC typical blood picture
-low platelets
-low fibrinogen
-raised APTT
-raised PT
-raised D-dimer
first line for reducing relapses in MS
natalizumab (monoclonal antibody)
investigation of choice for raised ICP
non-contrast CT
can a LP be performed in raised ICP
NO
if an anorexic patient comes in with confusion and dizziness what is the most important investigation
blood glucose
mechanism of action of antithrombin III
binds to heparin to deactivate factor Xa
most common side effect of memantine
constipation
where does vulvar cancer most commonly present
labia majora
how do 50% of cord prolapses happen
artificial rupture of membranes
what is cryoprecipitate mainly made of
factor VIII
first line for infertility in PCOS
clomifene
what drugs can cause aplastic anaemia
cytotoxics, chloramphenicol, sulphonamides, phenytoin, gold
most common type of Hodgkins lymphoma
nodular sclerosing
what is imatinib used for
chronic myeloid leukaemia
what is given to patients with polycythaemia rubra vera to reduce risk of blood clots
aspirin
rivaroxaban mechanism of action
direct factor Xa inhibitor
-its a DOAC
what does decrease in haptoglobin indicate
intravascular haemolysis
if a pregnant woman is vomiting and has a large for dates uterus what is likely
hydratidiform mole
first line treatment for ITP
oral prednisolone
how do you test for agranulocytosis
FBC
which cranial nerves can an acoustic shwannoma affect
cranial nerve VIII: vertigo, unilateral sensorineural hearing loss, unilateral tinnitus
cranial nerve V: absent corneal reflex
cranial nerve VII: facial palsy
ipsilateral CN III palsy and contralateral hemiparesis
weber’s syndrome
-PCA stroke
tear drop poikilocytes on film
myelofibrosis
premature ovarian insufficiency FSH levels
high
migraine prophylaxis for asthmatics
topiramate
can you give patients with myasthenia gravis beta blockers
they should be avoided
-causes worsening of the condition
do benzodiazepines inhibit or enhance GABA
enhance GABA
whats it called when someone takes ages to get to their answer of a question
circumstantiality
whats it called when someone answers the question and then keeps talking for ages
tangectality
what are the somatic symptoms for depression
early morning waking and changes in weight/appetite
what type of urinary incontinence can tricyclic antidepressants cause
overflow incontinence
how do you monitor LMWH
anti-Xa assay
monitoring for direct thrombin inhibitors (dabigatran) (new anticoagulants)
no monitoring required
what hormone is tested to test ovarian reserve prior to in vitro fertilisation
AMH
what causes receptive aphasia
wenicke’s
-can’t rly receive the info
what causes expressive
brocs’s
-can express what you want to say
what visual field defect would a lesion in the right optic tract cause
left homonymous hemianopia
what is delay in femoral pulse suggestive of in a newborn
coarctation of the aorta
mode of inheritance for beckers muscular dystrophy
X linked recessive
which hormone in pregnancy causes enlargement of the mammary glands of the breasts and prepares for lactation
prolactin
which STD on microscopy would show flagellated protozoa
trichomonas vaginalis
what cranial nerve can be injured by a pituitary adenoma
CN II
what drug for delirium secondary to a UTI
haloperidol
what nerve root for ankle reflex
S1
myasthenia gravis is antibodies against what?
POSTsynaptic Ach receptors
what hepatitis is spread via faecal oral route
A
a=anal
first line investigation for sickle cell
HPLC