year 3 passmed again Flashcards

1
Q

DIC typical blood picture

A

-low platelets
-low fibrinogen
-raised APTT
-raised PT
-raised D-dimer

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2
Q

first line for reducing relapses in MS

A

natalizumab (monoclonal antibody)

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3
Q

investigation of choice for raised ICP

A

non-contrast CT

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4
Q

can a LP be performed in raised ICP

A

NO

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5
Q

if an anorexic patient comes in with confusion and dizziness what is the most important investigation

A

blood glucose

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6
Q

mechanism of action of antithrombin III

A

binds to heparin to deactivate factor Xa

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7
Q

most common side effect of memantine

A

constipation

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8
Q

where does vulvar cancer most commonly present

A

labia majora

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9
Q

how do 50% of cord prolapses happen

A

artificial rupture of membranes

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10
Q

what is cryoprecipitate mainly made of

A

factor VIII

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11
Q

first line for infertility in PCOS

A

clomifene

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12
Q

what drugs can cause aplastic anaemia

A

cytotoxics, chloramphenicol, sulphonamides, phenytoin, gold

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13
Q

most common type of Hodgkins lymphoma

A

nodular sclerosing

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14
Q

what is imatinib used for

A

chronic myeloid leukaemia

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15
Q

what is given to patients with polycythaemia rubra vera to reduce risk of blood clots

A

aspirin

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16
Q

rivaroxaban mechanism of action

A

direct factor Xa inhibitor

-its a DOAC

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17
Q

what does decrease in haptoglobin indicate

A

intravascular haemolysis

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18
Q

if a pregnant woman is vomiting and has a large for dates uterus what is likely

A

hydratidiform mole

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19
Q

first line treatment for ITP

A

oral prednisolone

20
Q

how do you test for agranulocytosis

A

FBC

21
Q

which cranial nerves can an acoustic shwannoma affect

A

cranial nerve VIII: vertigo, unilateral sensorineural hearing loss, unilateral tinnitus
cranial nerve V: absent corneal reflex
cranial nerve VII: facial palsy

22
Q

ipsilateral CN III palsy and contralateral hemiparesis

A

weber’s syndrome
-PCA stroke

23
Q

tear drop poikilocytes on film

A

myelofibrosis

24
Q

premature ovarian insufficiency FSH levels

A

high

25
Q

migraine prophylaxis for asthmatics

A

topiramate

26
Q

can you give patients with myasthenia gravis beta blockers

A

they should be avoided
-causes worsening of the condition

27
Q

do benzodiazepines inhibit or enhance GABA

A

enhance GABA

28
Q

whats it called when someone takes ages to get to their answer of a question

A

circumstantiality

29
Q

whats it called when someone answers the question and then keeps talking for ages

A

tangectality

30
Q

what are the somatic symptoms for depression

A

early morning waking and changes in weight/appetite

31
Q

what type of urinary incontinence can tricyclic antidepressants cause

A

overflow incontinence

32
Q

how do you monitor LMWH

A

anti-Xa assay

33
Q

monitoring for direct thrombin inhibitors (dabigatran) (new anticoagulants)

A

no monitoring required

34
Q

what hormone is tested to test ovarian reserve prior to in vitro fertilisation

A

AMH

35
Q

what causes receptive aphasia

A

wenicke’s
-can’t rly receive the info

36
Q

what causes expressive

A

brocs’s
-can express what you want to say

37
Q

what visual field defect would a lesion in the right optic tract cause

A

left homonymous hemianopia

38
Q

what is delay in femoral pulse suggestive of in a newborn

A

coarctation of the aorta

39
Q

mode of inheritance for beckers muscular dystrophy

A

X linked recessive

40
Q

which hormone in pregnancy causes enlargement of the mammary glands of the breasts and prepares for lactation

A

prolactin

41
Q

which STD on microscopy would show flagellated protozoa

A

trichomonas vaginalis

42
Q

what cranial nerve can be injured by a pituitary adenoma

A

CN II

43
Q

what drug for delirium secondary to a UTI

A

haloperidol

44
Q

what nerve root for ankle reflex

A

S1

45
Q

myasthenia gravis is antibodies against what?

A

POSTsynaptic Ach receptors

46
Q

what hepatitis is spread via faecal oral route

A

A

a=anal

47
Q

first line investigation for sickle cell

A

HPLC