stuff that comes up alot Flashcards
what Ig is found in mucosa
IgA
what are ACEis contraindicated in
renal artery stenosis
side effect of spironolactone
gynaecomastia
what type of mouth disease do people with crohn’s have
stomatitis gangrenosum
what enzyme is affected in porphyria cutanea tarda
uroporphyrinogen decarboxylase
Cutanea = deCarboxylase
what does porphyria cutanea tarda cause build up of
coproporphyrinogen iii
presentation of porphyria cutanea tarda
blisters and fragility on hands and scalp
- hyperpigmentation
- hypertrichosis
- solar urticaria
- morphoea
what enzyme is affected in erythropoietic protoporphyria
ferrochelatase
E F off
presentation of erythropoietic protoporphyria
child crying in sunlight
what enzyme is affected in acute intermittent porphyria
PBG deaminase
intermittent =dea(ling with stuff)minase
presentation of acute intermittent porphyria
- abdo pain
- tachycardia
- hypertension
- dark or red urine
investigation for porphyria cutanea tarda
wood lamps
investigations for erythropoietin protoporphyria
- fluorocytes
- quantitative RBC porphyrins
what does acute intermittent porphyria cause a build up of
hydroxymethylbilane
what does shingles affect
dermatomes and nerve supplies
first line treatment for acne rosacea
topical metronidazole
what is ramsey hunt syndrome
shingles in the ear that old people get
-reactivation of varicella zoster virus in geniculate ganglion of CN VII
what is epidermolysis bullosa
breakdown of anchoring between epidermis and dermis
pathophysiology of paget’s disease of the bone
abnormal osteoclastic activity followed by increased osteoblastic activity
which drug causes reactivation of latent TB
TNFalpha inhibitor
- etanercept
- infliximab
what DMARD causes interstitial pneumonitis
methotrexate
what rheumatoid drug causes black tarry stool
NSAIDs