stuff that comes up alot Flashcards
what Ig is found in mucosa
IgA
what are ACEis contraindicated in
renal artery stenosis
side effect of spironolactone
gynaecomastia
what type of mouth disease do people with crohn’s have
stomatitis gangrenosum
what enzyme is affected in porphyria cutanea tarda
uroporphyrinogen decarboxylase
Cutanea = deCarboxylase
what does porphyria cutanea tarda cause build up of
coproporphyrinogen iii
presentation of porphyria cutanea tarda
blisters and fragility on hands and scalp
- hyperpigmentation
- hypertrichosis
- solar urticaria
- morphoea
what enzyme is affected in erythropoietic protoporphyria
ferrochelatase
E F off
presentation of erythropoietic protoporphyria
child crying in sunlight
what enzyme is affected in acute intermittent porphyria
PBG deaminase
intermittent =dea(ling with stuff)minase
presentation of acute intermittent porphyria
- abdo pain
- tachycardia
- hypertension
- dark or red urine
investigation for porphyria cutanea tarda
wood lamps
investigations for erythropoietin protoporphyria
- fluorocytes
- quantitative RBC porphyrins
what does acute intermittent porphyria cause a build up of
hydroxymethylbilane
what does shingles affect
dermatomes and nerve supplies
first line treatment for acne rosacea
topical metronidazole
what is ramsey hunt syndrome
shingles in the ear that old people get
-reactivation of varicella zoster virus in geniculate ganglion of CN VII
what is epidermolysis bullosa
breakdown of anchoring between epidermis and dermis
pathophysiology of paget’s disease of the bone
abnormal osteoclastic activity followed by increased osteoblastic activity
which drug causes reactivation of latent TB
TNFalpha inhibitor
- etanercept
- infliximab
what DMARD causes interstitial pneumonitis
methotrexate
what rheumatoid drug causes black tarry stool
NSAIDs
side effect of penicillamine
pneumonitis
who gets antiphospholipid syndrome
young autoimmune women presenting with recurrent miscarriages, DVT, PE
pathophysiology of sjogrens
lymphocytes invading glands
what other conditions is Bechet’s associated with
IBD and arthritis
what does the P stand for in CREST-P
pulmonary hypertension
which diabetic drug is weight neutral
DPP-fi inhibitors
-sitagliptin
symptoms of hypocalcaemia
- muscle spasms
- tingling
- nervousness
- chvokste sign
side effects of carbimazole
- neutropenia
- bone marrow suppression
- aganulocytosis
what tuning fork do you use for a diabetic foot exam
128-Hz
who gets PCOS
obese women
how do you treat endometrial polyps
-myomectomy
when do kids build a tower of 3 bricks and enjoy picture books
18 months
what is the mechanism of a live attenuated vaccination
pathogen alive but weakened
-it replicates and induces an immune reponse
what is an inactivate vaccine
dead pathogen or part of the pathogen given to stimulate immune reponse
how long does it take for scarlet fever to develop after tonsillitis
3 weeks
what is the left ear depicted as on an audiogram
an X
what is the right ear depicted as on an audiogram
O
what is bone depicted as on an audiogram
triangle
if when they lift their head they feel like they’re going to throw up what does this indicate
labyrinthitis
what antibiotic do you not give in a sore throat
amoxicillin
compression of what nerve is Bell’s palsy
CN VII
presentation of ramsey hunt syndrome
- auricular pain
- facial nerve palsy
- vesicular rash around ear
- vertigo
- tinnitus
diagnosis of BPPV
Hallpike
treatment of BPPV
epley manoeuvre
motor innervation of the ocular muscles
LR6-SO4-AO3
- lateral rectus CN 6
- superior oblique CN 4
- all others CN 3
what is seen in cranial nerve III palsy
oculomotor nerve
- eyes looking down and out
- fixed dilated pupil
- proptosis and ptosis
cranial nerve IV palsy
- eyes look upwards
- vertical diplopia
- cannot look down and in
- head held tilted
cranial nerve VI palsy
- horizontal diplopia
- eyes medially deviated
- cannot move laterally from midline
- convergent squint
what GFR is stage 3 CKD
30-60
first line investigation for hydrocele
doppler ultrasound with colour
what is the biggest cause of kidney disease
diabetes
diagnosis of BPH
trus with biopsy
what does secondary infection of eczema cause
monomorphic punched out lesions called dermatitis herpetiCUM
how do you treat dermatitis herpeticum
acyclovir
meningococcal pneumonitis symptoms
- really bad headache
- photophobia
- stiff neck
- fever
- nausea
- vomiting
