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Question 1

Drugs that displays TACHYPHYLAXIS

Answer 1

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M- Metoclopramide
E - Ephedrine
D - Dobutamine

L - LSD

C- Calcitonin
N - Nitroglycerin
N - Nicotine

H - Hydralazine
D - Desmopressin

Question 2

DRUGS THAT DISPLAY ZERO-ORDER ELIMINATION KINETICS

Answer 2

WHAT PET

W- Warfarin
H - Heparin
A - Aspirin
T - Tolbutamide

P - Phenytoin
E - Ethanol
T- Theophylline

Question 3

Drugs with narrow therapeutic index

Answer 3

WALA na Cyang TV PaPa

W -Warfarin
A - Aminoglycosides
L - Lithium
A - Amphotericin B
na
C - Carbamazepine
yang

T - Theophylline
V - Vancomycin

P - Phenytoin
P - Phenobarbital

Question 4

Diagnosis of MG (TENSILON TEST)

Answer 4

Edrophonium

Question 5

Treatment of MG

Answer 5

Pyridostigmine, Neostigmine

Question 6

Use for reversal of Atropine poisoning?

Answer 6

Physostigmine

Also used in Acute glaucome

S/e: Seizure

Question 7

Combination for Alzheimer’s dimentia

Answer 7

DM - AD

Donepezil + Memantine

Question 8

Treatment of Organophosphate poisoning?

Answer 8

Atropine - 1st choice

Pralidoxime

Question 9

Anti-Muscarinic effects

Answer 9

ALICE IN WONDERLAND

Hot as a hare - HYPERTHERMIA
Dry as a bone - DECREASED SECRETIONS
Red as a beet - CUTANEOUS VASODILATION
Blind as a bat - CYCLOPEGIA
Mad as a hatter - CNS TOXICITY

Question 10

Alpha-1 agonists

Answer 10

Phenylephrine, Pseudoephedrine

-ZOLINES (Oxymetazoline, Tetrahydroziline)

Question 11

Drugs used as DECONGESTANTS

Answer 11

Alpha-1 agonists

Phenylephrine
Pseudoephedrine
ZOLINES

Causes REBOUND NASAL CONGESTION or RHINITIS MEDICAMENTOSA (>5 days use)

Question 12

Associated with GASTROSCHISIS at 1st trimester use

Answer 12

Pseudoephedrine

Question 13

Alpha-1 agonist that causes ORTHOSTATIC HYPOTENSION

Answer 13

MiDOdrine

Question 14

Used for Alpha-1 agonist toxicity

Answer 14

Phentolamine

Question 15

Alpha-2 agonist used in Pre-eclampsia and gestational HPN

Answer 15

Methyldopa

Others: Guanfacine, guanabenz

Question 16

Most common side effect of METHYLDOPA

Answer 16

Sedation!!!

Others:
Hemolytic anemia - (+) Coombs test
Lactation - d/t increase prolactin
CNS effects (mental depression, vertigo, nightmares, impaired concentration)

Question 17

Irreversible alpha-1 antagonist

Answer 17

PhenoXybenzamine (X-irreversible)

REVERSIBLE alpha-1 antagonist: PHENTOLAMINE <3

Question 18

Pre-surgical drugs for Pheochromocytoma

Answer 18

PhenoXybenzamine: 1st line

Phentolamine

Question 19

Alpha-1 antagonist most selective for prostatic smooth muscle

Answer 19

Tamsulosin

Question 20

Alpha-1 antagonist that causes INTRAOPERATIVE FLOPPY IRIS SYNDROME (IFIS)

Answer 20

TAMSOLUSIN

Question 21

Alpha-1 antagonists are mainly used for

Answer 21

BENIGN PROSTATIC HYPERPLASIA

Also in HYPERTENSION (PRAZOSIN, TERAZOSIN ONLY)

Prazosin : Increases HDL!

Question 22

Non-selective beta blockers that may be used in PHEOCHROMOCYTOMA

Answer 22

C-L-N

CARVEDILOL
LABETALOL
NEBIVOLOL

has combined alpha and beta blockade

Question 23

Cardioselective B-1 blocker used in SUPRAVENTRICULAR TACHYCARDIA

Answer 23

ESMOLOOOOOL

Question 24

Beta-1 blocker with the SHORTEST HALFLIFE

Answer 24

ESMOLOL

Small-lol

Longest-acting: NADOLOL

Question 25

Absent in TIMOLOL and BETAXOLOL which make them useful in glaucoma

Answer 25

Local anesthetic activity or membrane-stabilizing activity