Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharma > BLOOD > Flashcards

BLOOD Flashcards

1
Q

Iron supplements are under what category?

A

Category A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Chelates excess iron

A

Deferoxamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Main stimulus for EPO production

A

Hypoxia-inducible factor 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

EPO is under what category?

A

Category C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Myeloid growth factors

A

FilGRASTIM (G-CSF)
SarGRAMOSTIM (GM-CSF)

GRA - granulocyte
STIM - stimulate
GRAM - granulocyte and myeloid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What organ produce thrombopoietin?

A

Liver

EPO -kidney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Megakaryocyte Growth Factor

A

Oprelvekin (IL-11)
TPO
Eltrombopag
Romiplastim

El(TROMBO)PAG - Thrombocyte
Romi(pla)(stim) - platelet stimulator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Used in chronic TTP

A

ELTROMBOPAG

Thrombopoietin-receptor agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Irreversible COX 1&2 inhibitor

A

Aspirin (Acetylsalicylic acid, ASA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Associated with Reye syndrome in children

A

Aspirin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Samter triad

A
  1. Asthma
  2. ASA sensitivity
  3. Nasal polyps
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

EptiFIBatide
TiroFIBan
Abciximab

A

Glycoprotein IIB/IIIA inhibitor

MOA: interferes with GPIIB/IIIA binding to fibrinogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Irreversibly inhibits binding of ADP to platelet receptors

A

ADP inhibitors

Clapidogrel
Ticlopidine
Prasugrel
Ticagrelor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ADP inhibitor that causes TTP

A

Ticlopidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ADP inhibitor that inhibits ADP subtype P2Y - allosteric antagonist

A

Ticagrelor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Inhibits phosphodiesterase III

A

PDE inhibitor

Dypiridamole
Cilostazol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Used only in refractory intermittent claudication in patients with PAD
Contraindicated in heart failure

A

Cilostazol

18
Q

Acid base disorder in ASPIRIN TOXICITY

A

Respiratory alkalosis with HAGMA

19
Q

Management for Heparin-induced thrombocytopenia (HIT)

A

Low molecular weight heparin (LMWH) - Fondaparinux
Direct thrombin inhibitor - Lepirudin

20
Q

Inhibits Vitamin K epoxide reductase

A

Warfarin

21
Q

Binds to thrombin’s active site

A

Direct thrombin inhibitors (-RUDIN, -GAT)

Lepirudin
Bivalirudin
Argatroban
Dabigatran

22
Q

Parameter used to monitor direct thrombin inhibitors

A

aPTT

23
Q

Monoclonal antibody used for reversal of Dabigatran toxicity

A

Idarucizumab

24
Q

Activates antithrombin III

A

Indirect thrombin inhibitors (Heparin, LMWH)

25
Q

DOC for anticoagulation during pregnancy

A

Heparin

26
Q

Antidote for Heparin toxicity

A

Protamine sulfate

27
Q

A heparinoid consisting of 80% heparin and 20% dermatan sulfate

A

Sulodexide

28
Q

Binds and potentiates effect of antithrombin III on factor Xa

A

Enoxaparin
Dalteparin
Tinzaparin
Fondaparinux

XA, PARIN

*does not require aPTT monitoring
*higher bioavailability and t 1/2

29
Q

Inhibit factor Xa

A

Oral direct factor Xa inhibitor

RivaroXaBAN
ApiXaBAN

Xa ban!!

*used esp after hip or knee surgery

30
Q

Oral anticoagulants

A

Warfarin
Dicumarol

31
Q

Used for chronic anticoagulation except during pregnancy

A

Warfarin

32
Q

Parameter used to monitor Warfarin

A

PT

33
Q

Antidote for Warfarin overdose

A

Vitamin K or FFP

34
Q

Active ingredient of most rat poison

A

Warfarin

35
Q

Tissue plasminogen activator analaog

A

Steptokinase
Alteplase
Urokinase
Reteplase

36
Q

Antidote for fibrinolytic drugs

A

Aminocaproic acid

37
Q

Competitively inhibits plasminogen activation by inhibiting tPA

A

Antiplasmin drugs: Aminocaproic acid

TRANEXAMIC ACID

38
Q

Treatment for ACUTE bleeding episodes

A

Tranexamic acid

39
Q

Used for prevention of hemorrhagic diatheses in newborns

A

Vitamin K

K1 - Phytonadione
K2 - Menaquinone

40
Q

ADH agonists

A

DVT

D - desmopressin
V - vasopressin
T - terlipressin

Pharma (31 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions