NSAIDs Flashcards

1
Q

Nonselective, irreversible COX 1&@ inhibitors
Reduces platelet production of TXA2

A

Aspirin

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2
Q

Prevent NSAID-induced gastritis

A

Misoprostol

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3
Q

Causes premature closure of PDA

A

Indomethacin

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4
Q

Post-surgical analgesic control, mainly used for analgesia

A

Ketorolac
Dexketoprofen

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5
Q

COX-2 selective NSAIDs

A

Celecoxib

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6
Q

COX-2 inhibitor withdrawn due to increased incidence of thrombosis

A

Rofecoxib
Valdecoxib

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7
Q

Preferential COX-2 selective inhibitor

A

Meloxicam

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8
Q

Selective COX-3 inhibitor

A

Paracetamol (acetaminophen)
Phenacetin

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9
Q

Causes renal papillary necrosis and interstitial nephritis

A

Phenacetin

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10
Q

Preferred antipyretic in children

A

Paracetamol

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11
Q

Antidote for paracetamol overdose

A

N-acetylcysteine

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