GENERAL ANESTHETICS Flashcards

1
Q

STAGES OF ANESTHESIA (GUEDEL’S SIGNS)

A

ADSM

Stage 1: Analgesia
Stage 2: Disinhibition
Stage 3. Surgical anesthesia
Stage 4: Medullary depression

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2
Q

Measure of concentration of inhaled anesthetics

A

Partial pressure or “tension”

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3
Q

Best measure of potency of inhaled anesthetics

A

Minimum Alveolar Anesthetic Concentration

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4
Q

Inhalation anesthetic that has a characteristic PUNGENT ODOR

A

Desflurane

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5
Q

Inhalation anesthetic that has a characteristic SWEET ODOR

A

Sevoflurane

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6
Q

Inhalation anesthetic contraindicated in asthmatic patients

A

Desflurane

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7
Q

Inhalation anesthetic contraindicated in patients with asthma

A

Desflurane

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8
Q

Inhalation anesthetic preferred in patients with asthma

A

Sevoflurane

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9
Q

Inhalation anesthetic that presents with CORONARY STEAL SYNDROME

A

Isoflurane

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10
Q

Inhalation anesthetic with characteristic spike-and-wave activity in EEG

A

Enflurane

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11
Q

Inhalation anesthetic with the highest propensity to cause HEPATITIS

A

Halothane

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12
Q

Inhalation anesthetic with the highest potency and lowest MAC

A

Methoxyflurane

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13
Q

Inhalation anesthetic for minor surgery and dental procedures

A

Nitric oxide

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14
Q

Inhalation anesthetic with the least potency and lest cardiotoxic effects

A

Nitrous oxide

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15
Q

Laughing gas (euphoria)

A

Nitrous oxide

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16
Q

Inhalation anesthetic are undesirable for patients with increased ICP except:

A

Nitrous oxide

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17
Q

ALL inhaled anesthetics depress normal cardiac contractility > decrease MAP via different mechanisms. Except:

A

Nitrous oxide

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18
Q

ALL inhaled anesthetics have a BRONCHODILATING properties except:

A

DESFLURANE

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19
Q

This condition results from mutation of RYANODINE RECEPTOR of the skeletal muscle that results to uncontrolled release of Ca2+ from SR. Occurs when susceptible individual are exposed to volatile anesthetics and succinylcholine

A

MALIGNANT HYPERTHERMIA

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20
Q

Most reliable test to establish susceptibility to malignant hyperthermia:

A

Caffeine-Halothane contracture test

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21
Q

Treatment for Malignant hyperthermia:

A

Dantrolene

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22
Q

IV anesthetic used for identification of epileptic foci

A

Barbiturates

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23
Q

IV anesthetic that is a potent vasoconstrictor best for patients with increased ICP

A

Barbiturates

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24
Q

IV anesthetic that causes ACUTE INTERMITTENT PORPHYRIA

A

Barbiturates

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25
Q

Intraarterial injection of this IV anesthetic can lead to gangrene

A

Barbiturate

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26
Q

IV anesthetic that causes HYPERALGESIA

A

Barbiturates

27
Q

IV anesthetic that causes post-operative respiratory depression (PORD)

A

Benzodiazepines

28
Q

Used as adjunct to inhalational anesthetics and IV opioid

A

Midazolam

29
Q

NMDA antagonist used for DISSOCIATIVE ANESTHESIA

A

Ketamine

30
Q

Causes post-op disorientation, hallucination, and excitation

A

Ketamine

31
Q

Pretreated with anticholinergic since this IV anesthetic causes lacrimation and salivation

A

Ketamine

32
Q

IV anesthetic used in asthmatic patients

A

Ketamine

33
Q

IV anesthetic that may be used in patients with limited cardiac or respiratory reserve

A

Etomidate

34
Q

IV anesthetic that causes ADRENOCORTICAL SUPPRESSION

A

Etomidate

35
Q

IV anesthetic used as induction agent of choice for unstable patients

A

Etomidate

36
Q

MOA of opioid

A

Interact with mu, delta, and kappa receptors for endogenous opioid peptides

37
Q

S/E of OPIOIDS

A

Respiratory depression

38
Q

Opioid analgesic that has a faster recovery among types

A

Remifentanil

39
Q

Antidote for opioid overdose

A

Naloxone

Alcohol + Opioid = Naltrexone

40
Q

Happens when FENTANYL, DROPERIDOL, NITROUS OXIDE are given together

A

Neuroleptanesthesia (analgesia + amnesia)

41
Q

IV anesthetic induction of choice (ICU and outpatient)

A

Propofol (Milk of Amnesia)

42
Q

IV anesthetic that causes pain at injection site and hypotension at induction

A

Propofol

43
Q

IV anesthetic that causes PARESTHESIA IN THE PERIANAL REGION

A

Fosprofolol

44
Q

May causes allergic reaction to asthmatic patients and patients with sulfa allergies

A

Propofol

45
Q

Alternative general anesthetic maintenance for patients susceptible to malignant hyperthermia

A

Propofol

46
Q

Has zero analgesic properties

A

Propofol

47
Q

Ester local anesthetic with the shortest half-life

A

Procaine

48
Q

Ester LA that causes METHEMOGLOBINEMIA

A

Benzocaine

49
Q

Present for TOPICAL use only

A

Benzocaine
Cocaine

50
Q

Used for surgeries involving ENT procedures

A

Cocaine

51
Q

ALL local anesthetics are vasodilators EXCEPT

A

Cocaine

52
Q

Causes mood elevation due to its dopamine receptor action

A

Cocaine

53
Q

Has intrinsic sympathomimetic activity (vasoconstriction)

A

Cocaine

54
Q

LA used for spinal anesthesia

A

Tetracaine

55
Q

LA that is Class 1B anti-arrhythmic drug, used for post-MI and for digitalis toxicity

A

LIDOCAINE!!!

56
Q

Limits systemic absorption of Lidocaine:

A

+ Epinephrine

57
Q

Commonly used in OPHTHALMIC preprations

A

Proparacaine

58
Q

Amide LA that causes METHEMOGLOBINEMIA

A

Prilocaine

Ester: Benzocaine

59
Q

Use with caution in pregnant patients and patients with cardiac disease because it may cause heart block, arrhythmia, and hypotension

A

Bupivacaine

60
Q

Most cardiotoxic amide LA

A

Bupivacaine

61
Q

Used to treat cardiotoxicity of Bupivacaine

A

Intralipid/Liposomal forms

62
Q

S(-) enantiomer of Bupivacaine > less cardiotoxic

A

Ropivacaine

63
Q

Amide LA with the longest half-life

A

Ropivacaine