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Pharma > SKELETAL MUSCLE RELAXANTS > Flashcards

SKELETAL MUSCLE RELAXANTS Flashcards

1
Q

Used for relaxation of respiratory muscles to facilitate mechanical ventilation in the ICU setting

A

Atracurium

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2
Q

Used for euthanasia, lethal injection, and stychrinine poisoning

A

Pancuronium

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3
Q

DOC for hemodynamically compromised

A

Cisatracurium
Vecuronium
Rocuronium

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4
Q

Side effect of all NON-DEPOLARIZING BLOCKERS

A

Respiratory paralysis

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5
Q

Reversal agent of NON-DEPOLARIZING BLOCKERS

A

Neostigmine

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6
Q

Prototype of NDB; poison arrow used in animal hunting

A

Tubocurarine

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7
Q

Causes moderate histamine release with hypotension

A

Tubocurarine
Mivacurium

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8
Q

Metabolized by PSEUDOCHOLINESTARASE

A

Mivacurium

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9
Q

NDB with short duration of action

A

Mivacurium

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10
Q

NDB with short duration of action

A

Mivacurium

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11
Q

NDB that undergoes Hoffman elimination

A

Atracurium
Cisatracurium

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12
Q

NDB ideal for hepatic patients

A

Atracurium

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13
Q

NDB eliminated via bile

A

Vecuronium

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14
Q

Reversal agent used for Vecuronium

A

Sugammadex

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15
Q

NDB for patients with renal impairment

A

Rocuronium

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16
Q

Has atropine-like effects such as tachycardia, hypertension and recurariztion

A

Pancuronium

17
Q

Depolarizing neuromuscular blocker

A

Succinylcholine

18
Q

Succinylcholine causes malignant hyperthermia when given together with what inhaled anesthetic?

A

Halothane

To dx:
Caffeine-Halothane contracture test

Tx:
Dantrolene

19
Q

Centrally-acting spasmolytics: GABA-B agonist

A

Baclofen

Facilitates spinal inhibition of motor neuron

20
Q

Centrally-acting spasmolytics: a2 agonist in the spinal cord

A

Tizanidine

21
Q

Centrally-acting spasmolytics: Inhibition of muscle stretch reflex

A

Orphenadrine

22
Q

Direct-acting muscle relaxant: Blocks RyR1 Ca2+ release channels in the SR of skeletal muscle

A

Dantrolene

23
Q

Direct-acting muscle relaxant: relaxes both skeletal and vascular smooth muscles

A

Eperisone

Pharma (31 decks)

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