SKELETAL MUSCLE RELAXANTS Flashcards
Used for relaxation of respiratory muscles to facilitate mechanical ventilation in the ICU setting
Atracurium
Used for euthanasia, lethal injection, and stychrinine poisoning
Pancuronium
DOC for hemodynamically compromised
Cisatracurium
Vecuronium
Rocuronium
Side effect of all NON-DEPOLARIZING BLOCKERS
Respiratory paralysis
Reversal agent of NON-DEPOLARIZING BLOCKERS
Neostigmine
Prototype of NDB; poison arrow used in animal hunting
Tubocurarine
Causes moderate histamine release with hypotension
Tubocurarine
Mivacurium
Metabolized by PSEUDOCHOLINESTARASE
Mivacurium
NDB with short duration of action
Mivacurium
NDB with short duration of action
Mivacurium
NDB that undergoes Hoffman elimination
Atracurium
Cisatracurium
NDB ideal for hepatic patients
Atracurium
NDB eliminated via bile
Vecuronium
Reversal agent used for Vecuronium
Sugammadex
NDB for patients with renal impairment
Rocuronium
Has atropine-like effects such as tachycardia, hypertension and recurariztion
Pancuronium
Depolarizing neuromuscular blocker
Succinylcholine
Succinylcholine causes malignant hyperthermia when given together with what inhaled anesthetic?
Halothane
To dx:
Caffeine-Halothane contracture test
Tx:
Dantrolene
Centrally-acting spasmolytics: GABA-B agonist
Baclofen
Facilitates spinal inhibition of motor neuron
Centrally-acting spasmolytics: a2 agonist in the spinal cord
Tizanidine
Centrally-acting spasmolytics: Inhibition of muscle stretch reflex
Orphenadrine
Direct-acting muscle relaxant: Blocks RyR1 Ca2+ release channels in the SR of skeletal muscle
Dantrolene
Direct-acting muscle relaxant: relaxes both skeletal and vascular smooth muscles
Eperisone
