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Pharma > ANTI-DEPRESSANTS > Flashcards

ANTI-DEPRESSANTS Flashcards

1
Q

Inhibits neuronal reuptake of serotonin and norepinephrine

A

TCA (Imipramine)

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2
Q

3Cs of TCA overdose:

A

Coma
Cardiotoxicity
Convulsion

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3
Q

Inhibits neuronal reuptake of serotonin by inhibiting SERT (serotonin transporter)

A

Selective serotonin reuptake inhibitor

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4
Q

DOC for Major Depressive Disorder

A

Fluoxetine (SSRI)

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5
Q

SSRI approved only for OCD

A

Fluvoxamine

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6
Q

SSRI indicated for premature ejaculation

A

Dapoxetine

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7
Q

SSRI involved in DISCONTINUATION SYNDROME

A

PS. Byeee

Paroxetine
Sertaline

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8
Q

SSRI that causes QT prolongation and is a teratogen (cardiac septal defects)

A

Citalopram

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9
Q

Antidepressant used for chronic pain and fibromyalgia

A

Serotonin-norepinephrine reuptake inhibitors (Venlafaxine, Duloxetine)

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10
Q

SRNI that may cause hepatotoxicity

A

Duloxetine

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11
Q

Causes “WITHDRAWAL SYNDROME” even if one missed dose

A

Serotonin-Norepinephrine reuptake inhibitor

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12
Q

Anti-depressant that has anti-cholinergic, anti-histamine, and alpha-blocking effect

A

Tricyclic antidepressants (Imipramine)

TRI-3 effects

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13
Q

MOA of Serotonin antagonist

A

Blocks 5-HT2 receptors

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14
Q

Used for HYPNOSIS

A

Trazodone

TRAPzodone
TRAYDORzodone

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15
Q

Strong NE reuptake inhibitor

A

Tetracyclic antidepressant (Amoxapine, Maprotiline)

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16
Q

Tetracyclic antidepressant that lowers seizure threshold

A

Amoxapine

17
Q

Antidepressant that inhibits neuronal uptake of dopamine and NE. Used for smoking cessation.

A

Bupropion

18
Q

Treatment for Serotonin syndrome

A

Cyproheptadine

19
Q

Serotonin antagonist that causes PRIAPRISM

A

Trazadone

20
Q

Serotonin antagonist that is hepatotoxic

A

Nefazodone

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