Urinary Tract Anti-infectives Flashcards

1
Q

Cystitis

A

Bladder inflammation

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2
Q

Prostatitis

A

Inflammation of the prostate gland

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3
Q

Pyelonephritis

A

Inflammation of the kidney nephron

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4
Q

Urinary tract infection (UTI)

A

Infection by pathogenic microorganisms of one or more structures if the urinary tract

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5
Q

Bladder UTI signs

A

Urgency, frequency, pressure, burning pain while urinating, and pain caused by spasm in the region of the bladder and subrapubic area

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6
Q

Most common drugs in treating UTIs

A

Amoxicillin, trimethoprim, nitrofurantoin, urinary analgesics

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7
Q

Urinary analgesics use

A

UTIs and long term interstitial cystitis

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8
Q

UTI Drugs MOA

A

Interfere with bacterial multiplication in the urine

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9
Q

Phenazopyridine MOA

A

Topical analgesic effect on the lining of the urinary tract.

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10
Q

Phenazopyridine use

A

UTI

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11
Q

UTI Drugs side effects

A

Anorexia, nausea, vomiting, diarrhea, abdominal pain, stomatitis, drowsiness, dizziness, headache, blurred vision, weakness and peripheral neuropathy, rash, pruritus, photosensitivity, leg cramps

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12
Q

Nitrofurantoin side effects

A

Acute and chronic pulmonary reactions

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13
Q

Phenazopyridine side effects

A

Discolor urine (dark orange to brown)

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14
Q

UTI Drugs contraindications

A

Pregnancy (cat C), lactation

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15
Q

Nitrofurantoin precautions

A

Pregnancy (cat B) , cerebral atherosclerosis p, diabetes, glucose-6-phosphate dehydrogenase deficiency

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16
Q

UTI Drugs precautions

A

Renal or hepatic dysfunction

17
Q

Methenamine contraindications

A

Allergy to tartrazine

18
Q

Menthenamine precautions

A

Gout

19
Q

Sulfamethizole interactions

A

Oral anticoagulants increase risk of bleeding

20
Q

Nitrofurantoin interactions

A

Nitrofurantoin absorption decreases with magnesium trisilicate and magaldrate, and anticholinergic increase nitrofurantoin absorption

21
Q

Fosfomycin interactions

A

Metoclopramide lowers plasma concentration and urinary tract excretion of fosfomycin

22
Q

Phenazopyridine restrictions

A

Shouldn’t be taken for more than 2 days when combined with an antibacterial to treat a UTI

23
Q

UTI Drugs ex

A

Amoxicillin, fosfomycin, methenamine, nitrofurantoin, trimethoprim

24
Q

Urinary analgesics ex

A

Phenazopyridine, pentosan