Adrenergic Drugs Flashcards

1
Q

Adrenergic

A

Pertaining to the sympathetic branch of the nervous system, which controls heart rate, breathing rate, and ability to divert blood to the skeletal muscles

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2
Q

Autonomic nervous system (ANS)

A

Division of the peripheral nervous system concerned with Functions essential to the life of the organism and not consciously controlled (blood pressure, heart rate, GI activity)

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3
Q

Catecholamine

A

Neurotransmitters that are released during the body’s stress response and include norepinephrine, epinephrine, and dopamine

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4
Q

Extravastation

A

Escape of fluid from a blood vessels into surrounding tissue

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5
Q

Neurotransmitter

A

Chemical substances released at the nerve ending that facilitate the transmission of nerve impulses

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6
Q

Norepinephrine

A

Neurotransmitter that transmits impulses across the sympathetic branch of the autonomic nervous system

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7
Q

Parasympathetic

A

Pertaining to the part of the autonomic nervous system concerned with conserving body energy (sowing heart rate, digesting food, and eliminating waste)

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8
Q

Peripheral nervous system (PNS)

A

All nerves outside of brain and spinal cord

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9
Q

Shock

A

Inadequate blood flow to the bodily tissues

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10
Q

Stroke volume

A

The volume of blood ejected from a ventricle at each heart beat

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11
Q

Vasopressors

A

Drugs that raise the blood pressure

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12
Q

Sympathomimetic

A

Drugs that mimic the actions of the sympathetic nervous system

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13
Q

What do adrenergic drugs do to CNS

A

Wakefulness, quick reaction to stimuli, quickened reflexes

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14
Q

What do adrenergic drugs do to ANS

A

Relaxation of smooth muscles of bronchi, constriction of blood vessels, sphincters of the stomach, dilation of coronary blood vessels, and decrease in gastric motility

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15
Q

What do adrenergic drugs do to Heart

A

Increase heart rate

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16
Q

What do adrenergic drugs do to metabolism

A

Increase glucose use, and liberation of fatty acids from adipose tissue

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17
Q

Receptor selectivity of isoproterenol

A

Beta receptors

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18
Q

Receptor selectivity of epinephrine

A

Non selective

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19
Q

Alpha 1 receptor effect

A

Vasoconstriction of peripheral blood vessels

20
Q

Alpha 2 receptor effect

A

Regulates release of neurotransmitters, decreases tone, motility, and secretions of GI tract

21
Q

Beta 1 receptor effect

A

Increased heart rate, increased force of myocardial contraction

22
Q

Beta 2 receptor effects

A

Vasodilation of peripheral vessels, bronchodilation

23
Q

Adrenergic drugs uses

A

Hypovolemic and septic shock, hypotension, control of superficial bleeding during mouth, nose throat, and skin surgery, cardiac decompensation and arrest, allergic reactions, temporary treatment of heart block, ventricular arrhythmia, respiratory distress, nasal congestion, glaucoma

24
Q

Short acting beta 2 Agonists use

A

Acute respiratory symptom relief

25
Short acting beta 2 Agonists ex
Albuterol, epinephrine, levalbuterol, metaproterenol, terbutaline
26
Long acting beta 2 Agonists use
Long term respiratory management
27
Long acting beta 2 Agonists ex
Arformoterol, formoterol, indacaterol, salmeterol
28
Alpha 2 adrenergic agonists use
Optic agents
29
Alpha 2 adrenergic Agonists ex
Brimonidine tartrate
30
Sympathomimetics ex
Apraclonidine, dipivefrin, epinephrine
31
Sympathomimetics use
Bronchodilators in the treatment of respiratory problems, or topically in the treatment of glaucoma
32
Hypovolemic shock
Occurs when blood volume is severely diminished (hemorrhage, fluid loss caused by burns, dehydration, excess diuresis)
33
Cardiogenic-obstructive shock
Occurs when cardiac output is insufficient and perfusion to the vital organs can’t be maintained
34
Distributive (vasogenic) shock
Occurs when there are changes to the blood vessels causing dilation, but no additional blood volume, the blood is redistributed in the body.
35
Septic shock
Circulatory insufficiency resulting from overwhelming infection
36
Anaphylactic shock
Hypersensitivity resulting in massive systemic vasodilation
37
Neurogenic shock
Interference with PNS control of blood vessels
38
Shock side effects
Decrease in cardiac output, decrease in arterial blood pressure, reabsorption of water by the kidneys, decrease in the exchange of oxygen and carbon dioxide in the lungs, increase in carbon dioxide and decrease in oxygen in the lungs
39
Management of shock
Aimed at roviding basic life support, and correcting underlying cause, and initial drug given would be a vasopressor
40
Adrenergic drugs side effects
Cardiac arrhythmia (bradycardia or tachycardia), headache, nausea, vomiting, increased blood pressure
41
Epinephrine isn’t for
Elderly
42
Isoproterenol contraindications
Tachyarrhythmias, heart block caused by digitalis toxicity, ventricular arrhythmia, and angina
43
Epinephrine contraindications
Narrow angle glaucoma, and as a local anesthetic adjunct in fingers and toes
44
Norepinephrine contraindications
Hypotension from blood volume deficits
45
Midorine side effects
Severe hypotension in patients who are lying down
46
Adrenergic drugs precautions
Coronary insufficiency, cardiac arrhythmia, angina lector is, diabetes, hyperthyroidism, occlusive vascular disease, or prostatic hypertrophy, pregnancy (cat C)
47
Adrenergic drugs interactions
Antidepressants increase sympathomimetic effect, oxytocin increase risk of hypertension