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Pharmacology HOSA > Male And Female Hormones > Flashcards

Male And Female Hormones Flashcards

1
Q

Anabolism

A

Tissue building process

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2
Q

Androgens

A

Male hormones, responsible for sexual maturity and characteristics

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3
Q

Catabolism

A

Tissue depletion process

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4
Q

Estrogen

A

Female hormones, responsible for sexual maturity and characteristics

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5
Q

Gynecomastia

A

Male breast enlargement

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6
Q

Progesterone

A

Female hormone produced by the corpus luteum that works in the uterus along with estrogen to prepare the uterus for possible conception

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7
Q

Testosterone

A

Primary male sex hormone, acts to stimulate development of the make reproductive organs and secondary sex characteristics

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8
Q

Virilization

A

Acquisition of male sexual characteristics by a woman

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9
Q

Treating gender dysphoria

A

Counseling, surgical procedures, growth hormones, antihormone drugs, hormone replacement

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10
Q

Anabolic steroids MOA

A

promote anabolism and reverse catabolism, have a minimal effect in the accessory sex organs and secondary sex characteristics

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11
Q

Androgen therapy use

A

May be given as replacement therapy for testosterone deficiency, hypogonadism (failure of the testes to develop), delayed puberty, development of testosterone deficiency after puberty, postmenopausal metastatic breast carcinoma, and premenopausal hormone dependent metastatic breast carcinoma,

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12
Q

Transdermal testosterone system use

A

Replacement therapy when endogenous testosterone is deficient

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13
Q

Anabolic steroids use

A

Management of anemia of renal insufficiency, control of metastatic breast cancer in women, promotion of weight gain in those with weight loss after surgery, trauma, or infections

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14
Q

Androgens side effects in men

A

Gynecomastia, testicular atrophy, inhibition of testicular function, impotence, enlargement of the penis, nausea, vomiting, jaundice, headache, anxiety, male pattern baldness, acne and depression, fluid and electrolyte imbalances, and phosphate retention

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15
Q

Androgens side effects in women preparing for breast carcinoma side effects

A

Amenorrhea, menstrual irregularities, virilization (facial hair, deeper voice, and enlargement of clitoris), male pattern baldness, acne

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16
Q

Anabolic steroids side effects

A

Virilization in women, acmes in both sexes, nausea, vomiting, diarrhea, fluid and electrolyte imbalances, testicular atrophy, jaundice, anorexia, muscle cramps, blood filled cysts of the liver and spleen, malignant and benign liver tumors, increased risk of atherosclerosis

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17
Q

Anabolic steroids Sid effects in healthy people

A

Severe mental changes, uncontrolled rage, severe depression, suicidal tendencies, malignant and benign liver tumors, aggression, increased risk of atherosclerosis, inability to concentrate, and personality changes

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18
Q

Male hormones contraindications

A

Liver disorders, serious cardiac disease, men with prostrate gland disorders (prostate carcinoma and prostrate enlargement), pregnancy (cat X), and lactation

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19
Q

Anabolic steroids contraindications

A

Enhancing physical appearance or athletic performance,

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20
Q

Anabolic steroids precautions

A

Older men because if increased risk of prostate enlargement and prostate cancer

21
Q

Male hormones interactions

A

Increased antidiuretic effect anticoagulants, imipramine and androgen increase risk for paranoid behavior, sulfonylureas and anabolic steroids increase risk for hypoglycemia

22
Q

Androgens diabetes considerations

A

Blood glucose levels should be measured frequently because blood glucose tolerance may be altered

23
Q

Male hormones elderly considerations

A

Elderly with cardiac problems or kidney disease are at increased risk for sodium and water retention with androgens and anabolic steroids

24
Q

Estrogens MOA

A

Important in the development and maintenance of the female reproductive system and the primary and secondary sex characteristics, fluid retention, protein anabolism, thinning of the cervicales mucus, inhibition or facilitation of ovulation,

25
Q

Progestins MOA

A

Necessary for the development of placenta and inhibit the secretion of pituitary gonadotropins, which prevents the maturation of the ovarian follicle and ovulation

26
Q

Estrogens use

A

In combination with progesterones as a contraceptive, or in postmenopausal women as estrogen replacement therapy (ERT) or in combination with progesterone as hormone replacement therapy (HRT)

27
Q

Progestins use

A

Treatment of amenorrhea, endometriosis, and functional uterine bleeding, and as oral contraceptives

28
Q

4 types of estrogen and progestin combination contraceptives

A

Monophasic, biphasic, triphasic, and quad-phasic

29
Q

Estrogens side effects

A

Headache, migraine, dizziness, depression, dermatitis, pruritus, chloasma, melasma, vomiting, bloating, abdominal cramps, breakthrough bleeding, withdrawal bleeding, spotting, change in menstrual flow, dysmenorrhea, PMS, amenorrhea, vaginal candidiasis, cervicales erosion, vaginitis, pain at injection site, sterile abscesses, steepening of corneal curvature, intolerance to contact lenses, edema, rhinitis, changes in libido, breast pain, enlargement and tenderness, reduced card tolerance, weight gain or loss, generalized and skeletal pain, venous thromboembolism, pulmonary embolism

30
Q

Warnings associated with the administration of estrogen

A

Increased risk of endometrial cancer, gallbladder disease, hypertension, hepatic adenoma, cardiovascular disease, thromboembolic disease, hypercalcemia in people with breast cancer and bone metastases

31
Q

Progestins side effects

A

Breakthrough bleeding, spotting, changes in menstruales flow, amenorrhea, breast tenderness, edema, weight gain or loss, acne, chloasma, melasma, insomnia, mental depression

32
Q

Contraceptive hormones side effects

A

Vary depending on estrogen and progestin content

33
Q

Estrogen contraindications

A

Breast cancer(except metastatic disease), estrogen dependent neoplasms, undiagnosed abnormal genital bleeding, thromboembolic disorders, pregnancy (cat X)

34
Q

Progestin contraindications

A 
Breast cancer (except for metastatic disease), estrogen dependent neoplasms, undiagnosed abnormal genital bleeding, thromboembolic disorders, pregnancy (cat 
X), cerebral hemorrhage, impaired liver function
35
Q

Estrogen precautions

A

Gallbladder disease, hypercalcemia, cardiovascular disease, liver impairment. Cardiovascular complications are more likely in women who smoke and use estrogen

36
Q

Progestin precautions

A

History of migraines, epilepsy, asthma, and cardiac or renal impairment

37
Q

Estrogen excess signs

A

Nausea, bloating, cervical mucus increase, numerous polyps, hypertension, migraines, breast fullness or tenderness, edema

38
Q

Progestin excess signs

A

Increased appetite, weight gain, tiredness, hypomenorrhea, acne, oily scalp, hair loss, hirsutism, depression, monilial vaginitis, breast regression

39
Q

Estrogen deficiency signs

A

Early or midchle breakthrough bleeding, spotting, hypomenorrhea, melasma

40
Q

Progestin deficiency signs

A

Late breakthrough bleeding, amenorrhea, hypermenorrhea

41
Q

Oral contraceptives warnings

A

Cigarette smoking increases risk of cardiovascular side effects, hepatic adenomas, tumors, visual disturbances, gallbladder disease, hypertension, and fetal abnormalities

42
Q

Estrogens interactions

A

Decreased anticoagulant effect (oral), increased TCA effects, rifampin increases risk of breakthrough bleeding, hydantoins increase risk of breakthrough bleeding and pregnancy

43
Q

Progestins interactions

A

Anticonvulsants and rifampin decrease progestin effectiveness, and penicillins and tetracyclines decrease effectiveness of oral contraceptives containing progestin

44
Q

Oral contraceptives considerations

A

Increased risk of postoperative thromboembolic complications, if possible, discontinue 4 weeks before surgery

45
Q

Androgens ex

A

Fluoxymesterone, methyltestosterone, testosterone,

46
Q

Anabolic steroids ex

A

Nandrolone, oxymetholone, oxandrolone

47
Q

Estrogens ex

A

Estradiol cypionate, transdermal estradiol, estropipate

48
Q

Progestins ex

A

Progesterone, medroxyprogesterone, norethindrone

Pharmacology HOSA (37 decks)

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