Antifungals And Antiparasitics

Question 1

Candidiasis

Answer 1

Infection if the skin or mucous membrane with the yeast Candida albicans

Question 2

Cinchonism

Answer 2

Qunidine toxicity or poisoning

Question 3

Fungicidal

Answer 3

Deadly to fungi

Question 4

Fungistatic

Answer 4

Pertaining to agents that retard growth of fungi

Question 5

Fungus

Answer 5

Single cell, colorless plant that lacks chlorophyll, such as yeast or mold

Question 6

Helminthiasis

Answer 6

Invasion by helminth s (worms)

Question 7

Mycotic infections

Answer 7

Infections caused by fungi

Question 8

Parasite

Answer 8

Organism living in or on another organism (host) without contributing to the survival or well being of host

Question 9

Thrush

Answer 9

Candidiasis of the mouth

Question 10

Systemic fungal infections

Answer 10

Serious infections that occur when the fungi gain entrance into the interior of the body, can grow in lungs, Braun or GI tract

Question 11

Where dies candidiasis affect patients

Answer 11

Mouth (thrush), affects women in vulvovaginal area, immunocompromised patients with chronic conditions in the perenium, oral cavity, or systemically

Question 12

Who is at the highest risk for Candidal infections

Answer 12

Diabetes, pregnant, oral contraceptives, antibiotics, or corticosteroids

Question 13

Antifungal actions

Answer 13

Fungicidal or fungistatic. Amphotericin B, isavuconazonium, miconazole, nystatin, voriconazole, micafungin, and ketoconazole have an effect on the cell membrane of the fungus

Question 14

Topical antifungals

Answer 14

Butenafine, ciclopirox, clotrimazole, econazole, efinaconazole, miconazole, naftifine, oxiconazole, sulconazole, tavaborole

Question 15

Antifungal uses

Answer 15

Superficial and deep fungal infections, systemic infections such as aspergillosis, candidiasis, and cryptococcal menengitis, superficial infections of nail beds, and oral, anal, and vaginal areas

Question 16

Miconazole

Answer 16

Treats vulvovaginal yeast infections

Question 17

Vaginal antifungal Drugs

Answer 17

Clotrimazole, miconazole, nystatin, terconazole, tioconazole

Question 18

Amphotericin B interactions

Answer 18

Corticosteroids increase risk for severe hypokalemia, digoxin increases risk of digitalis toxicity, aminoglycosides increase risk of nephrotoxicity, cyclosporine increases risk of nephrotoxicity, flucytosine causes drug toxicity, and miconazole decreases effectiveness of amphotericin B

Question 19

Fluconazole interactions

Answer 19

Oral hypoglycemics increase their own effect, phenytoin decreases its own effectiveness

Question 20

Griseofulvin interactions

Answer 20

Barbiturates decreases their own effect, oral contraceptives decrease their own effectiveness salicylates decrease their own serum level

Question 21

Itraconazole interactions

Answer 21

Digoxin and cyclosporine elevate blood levels of itraconazole, phenytoin and histamine antagonists decrease blood levels of itraconazole, isoniazid and rifampin decrease blood levels of itraconazole

Question 22

Ketoconazole interactions

Answer 22

Histamine antagonist and antacids decreases absorption of ketoconazole, rifampin or isoniazid decrease blood levels of ketoconazole

Question 23

Posaconazole interactions

Answer 23

Cimetidine decreases posaconazole blood levels, phenytoin increases its own effectiveness, rifabutin decrease blood levels of posaconazole, stations increase their own effectiveness

Question 24

Voriconazole interactions

Answer 24

Methadone, tacrolimusm ,the statins, benzodiazepines, CCB’s increase effectiveness of voriconazole, sulfonylureas cause hypoglycemia, vinca alkaloids increase risk of neurotoxicity

Question 25

Micafungin interactions

Answer 25

Sirolimus increases risk of immunosuppression, nifedipine increases risk of its own toxicity

Question 26

Terbinafine interactions

Answer 26

Beta blockers and antidepressants increase their own effectiveness

Question 27

Fluconazole, ketoconazole, itraconazole, voriconazole and griseofulvin common interaction

Answer 27

Warfarin increases risk of bleeding

Question 28

Antifungals adverse reactions

Answer 28

Headache, rash, anorexia, malaise, abdominal, joint, or muscle pain, nausea, vomiting, diarrhea

Question 29

Antifungals contraindications

Answer 29

Pregnancy and lactation, but only used in life threatening situations when risk to fetus is outweighed

Question 30

Griseofulvin contraindications

Answer 30

Sever liver disease

Question 31

Voriconazole contraindications

Answer 31

When taking terfenadine, astemizole, sirolimus, rifampin, rifabutin, carbamazepine, ritonavir, ergot alkaloids, or long acting barbiturates, cisapride, pimozide, or quinidine

Question 32

Itraconazole contraindications

Answer 32

Cisapride, pimozide, quinidine, shouldn’t be used to treat fungal nail infections in patients with a history of heart failure

Question 33

Antifungals precautions

Answer 33

Renal dysfunction or hepatic impairment

Question 34

Amphotericin B precautions

Answer 34

Caution with electrolyte imbalances or antineoplastic Drugs, given only under close supervision, can cause impaired comfort, IV solution is light sensitive

Question 35

Griseofulvin precautions

Answer 35

Penicillin

Question 36

Itraconazole precautions

Answer 36

HIV, or hypochlorhydria

Question 37

Antihelmintic drugs action

Answer 37

Kill parasites

Question 38

Albendazole MOA

Answer 38

Interfere with the synthesis is the parasites microtubukes

Question 39

Albendazole use

Answer 39

Larval forms of pork tapeworm, liver, lung, and peritoneum disease caused by dog tapeworm

Question 40

Mebendazole MOA

Answer 40

Blocks uptake of glucose by worm

Question 41

Mebendazole use

Answer 41

Whip worm, pinworm, roundworm, American hookworm, and the common hookworm

Question 42

Pyrantel MOA

Answer 42

Paralyze helminth

Question 43

Pyrantel use

Answer 43

Roundworm and pinworm

Question 44

Anthelmintic adverse reactions

Answer 44

Drowsy, dizzy, nausea, vomiting, diarrhea, abdominal pain, cramps

Question 45

Pyrantel side effects

Answer 45

Rash

Question 46

Anthelmintic contraindications and precautions

Answer 46

Caution in pregnancy (cat C), and lactating, patients with hepatic or renal impairment, and patients with malnutrition or anemia

Question 47

Anthelmintic interactions albendazole

Answer 47

Dexamethasone and cimetidine increase effectiveness of albendazole

Question 48

Mebendazole interactions

Answer 48

Hydantoins and carbamazepine lower levels of mebendazole

Question 49

Antiprotozoal drugs actions

Answer 49

Interfere with life cycle of the protozoan

Question 50

Antiprotozoal Drugs uses

Answer 50

Malaria,giardiasis, toxoplasmosis, intestinal amebiasis, STI's (trichomoniasis), pneumocystis pneumonia (PCP), preventing malaria

Question 51

Antiprotozoal adverse reactions

Answer 51

Anorexia, nausea, vomiting, diarrhea, abdominal cramps, headache, dizzy, visual disturbance, tinnitus, hypotension, changes detected on ECG, cinchonism (symptoms: tinnitus, headache, GI disturbance, and visual disturbance)

Question 52

Metronidazole side effects

Answer 52

Peripheral neuropathy

Question 53

Paromycin side effects

Answer 53

Nephrotoxicity and ototoxicity

Question 54

Most antiprotozoals are pregnancy cat

Answer 54

C

Question 55

Metronidazole is pregnancy cat

Answer 55

B

Question 56

Nitazoxanide pregnancy cat

Answer 56

B

Question 57

Doxycycline pregnancy cat

Answer 57

D

Question 58

Quinine pregnancy cat

Answer 58

X

Question 59

Quinine contraindications

Answer 59

Myasthenia gravis

Question 60

Antiprotozoal precautions

Answer 60

Children, lactation, people with renal or hepatic impairment, or bone marrow depression

Question 61

Metronidazole precautions

Answer 61

seizure disorders, severe hepatic impairment, Blood dyscrasias, bowel disease, history of alcohol dependency

Question 62

Nitazoxanide precautions

Answer 62

Blood dyscrasisa, seizure disorders, bowel disease, history of alcohol dependency

Question 63

Antimalarial interactions

Answer 63

Antacids and iron decrease absorption if the antimalarial

Question 64

Antiprotozoal interactkons

Answer 64

Increased risk of digoxin toxicity

Question 65

Metronidazole interactions

Answer 65

Cimetidine decreases metabolism of metronidazole, and phenobarbital increases metabolism of metronidazole,

Question 66

Quinine interactions

Answer 66

Warfarin has an increased risk of bleeding

Question 67

Parasitic invasion of body can cause

Answer 67

Diarrhea and risk for deficient fluid volume