Cholinergic Blocking Drugs Flashcards

1
Q

Anticholinergic

A

Blocks the neurotransmission of the parasympathetic nervous system

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2
Q

Cholinergic blocking

A

Blocked the effect of the parasympathetic branch of the ANS

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3
Q

Cycloplegia

A

Paralysis of the ciliary muscle, resulting in an inability to focus the eye

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4
Q

Mydriasis

A

Dilation of the pupil

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5
Q

Parasympatholytic

A

Blocking the parasympathetic nervous system

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6
Q

Xerostomia

A

Drying of oral secretions

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7
Q

Cholinergic blocking drugs MOA

A

Inhibit activity of acetylcholine at the parasympathetic nerve synapse, so that impulses traveling along the parasympathetic nerve can’t pass from the nerve endings to an organ or structure

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8
Q

Side effects of cholinergic blocking drugs in elderly

A

Excitement, agitation, mental confusion, drowsiness, urinary retention

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9
Q

Cholinergic blocking drugs uses

A

Uretersl or biliary Colin and bladder overactivity, pylorospasm, peptic ulcer, vagal nerve induced bradycardia, and Parkinsonism, and preoperative reduction of oral secretions

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10
Q

Severity of adverse reactions of cholinergic blocking drugs is dependent on

A

Dose

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11
Q

Cholinergic blocking drugs GI side effects

A

Dry mouth, nausea, vomiting, difficulty swallowing, heartburn, constipation

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12
Q

Cholinergic blocking drugs CNS system side effects

A

Headache, flushing, nervousness, drowsiness, weakness, insomnia, nasal congestion, fever

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13
Q

Cholinergic blocking drugs visual reactions

A

Blurred vision, mydriasis, photophobia, cycloplegia, increased ocular tension

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14
Q

Cholinergic blocking drugs genitourinary system side effects

A

Urinary hesitancy and retention, dysuria

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15
Q

Cholinergic blocking drugs cardiovascular system side effects

A

Palpitations, Brady cardia (after low doses of atropine), tachycardia (after high doses of atropine)

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16
Q

Cholinergic blocking drugs side effects general

A

Urticaria, decreased sweat production, anaphylactic shock, rash

17
Q

Patients taking cholinergic blocking drugs in hot summer months should watch for

A

Signs of heat prostration (fever, tachycardia, flushing, warm and dry skin, mental confusion)

18
Q

Cholinergic blocking drugs contraindications

A

Glaucoma, myasthenia gravis, tachyarrhythmia, myocardial infarction, and heart failure (unless bradycardia is present)

19
Q

Cholinergic blocking drugs precautions

A

GI infections, benign prostatic hypertrophy, urinary retention, hyperthyroidism, hepatic or renal disease, and hypertension, pregnancy (cat C)

20
Q

Atropine precautions

A

Asthma

21
Q

Cholinergic blocking drugs interactions

A

Decreased effectiveness of antibiotics and antifungals, meperidine, flurazepam, phenothiazines and TCAs decrease effect of cholinergic blocker, decrease effectiveness of haloperidol, increased serum levels of digoxin

22
Q

Cholinergic blocking drugs ex

A

Atropine, dicyclomine, glycopyrrolate, mepenzolate, methscopolamine, propantheline, scopolamine, trimethobenzamide

23
Q

Cholinergic blocking urinary antipasmodics ex

A

Darifenacin, fesoterodine, flavoxate, oxybutynin, solifenacin, tolterodine, trospium

24
Q

Cholinergic blocking drugs for Parkinson’s disease

A

Benztropine mesylate, diphenhydramine, trihexyphenidyl

25
Q

Cholinergic blocking drugs for acute respiratory symptom relief

A

Aclidinium, ipratropium, tiotroplum, umeclidinium