Cholinergic Drugs

Question 1

Acetylchoninesterase

Answer 1

Enzyme that can inactivate the neurotransmitter acetylcholine

Question 2

Cholinergic crisis

Answer 2

Cholinergic drug toxicity

Question 3

Micturition

Answer 3

Voiding of urine

Question 4

Miosis

Answer 4

Constriction of the pupil if the eye

Question 5

Muscarinic receptor

Answer 5

Neurological receptors that stimulate smooth muscle in the parasympathetic branch of the ANS

Question 6

Myasthenia gravis

Answer 6

Neuromuscular condition characterized by weakness and fatigability of the muscles

Question 7

Nicotinic receptors

Answer 7

Neurological receptors that stimulate skeletal muscles in the parasympathetic branch of the ANS

Question 8

Parasympathomimetic

Answer 8

Mimic the activity of the parasympathetic nervous system

Question 9

Direct acting cholinergic MOA

Answer 9

Act like the neurotransmitter acetylcholine

Question 10

Direct acting cholinergic uses

Answer 10

Urinary retention

Question 11

Indirect acting cholinergic

Answer 11

Drugs that prolong the activity of acetylcholine

Question 12

Anti cholinesterase drugs use

Answer 12

Symptoms of myasthenia gravis

Question 13

Cholinergic drugs uses

Answer 13

Urinary retention and myasthenia gravis

Question 14

Cholinergic Drugs side effects

Answer 14

Nausea, diarrhea, abdominal cramps, salivation, flushing of the skin, cardiac arrhythmias, muscle weakness

Question 15

Cholinergic Drugs contraindications

Answer 15

Asthma,peptic ulcer disease, coronary artery disease, and hyperthyroidism

Question 16

Bethanechol contraindications

Answer 16

Mechanical obstruction of the GI or genitourinary tracts

Question 17

Ophthalmic cholinergic preparations contraindications

Answer 17

Secondary glaucoma,iritis, corneal abrasion, or any acute inflammatory eye disease

Question 18

Cholinergic Drugs precautions

Answer 18

Hypertension, epilepsy, cardiac arrhythmias, bradycardia, recent coronary occlusion, and megacolon, pregnancy (cat C), lactation, or in children

Question 19

Cholinergic Drugs interactions

Answer 19

Aminoglycosides increase neuromuscular blocking effect, corticosteroids decrease effect of cholinergic, multiple cholinergic drugs become synergistic, use with anticholinergic drugs becomes antagonistic

Question 20

Antidote for overdose of cholinergic drugs

Answer 20

Atropine

Question 21

Cholinergic Drug overdosage signs

Answer 21

Muscle rigidity and spasm, salivation, and clenching of the jaw

Question 22

Cholinergic underdosage signs

Answer 22

Rapid fatigability if the muscles, drooping of the eyelids, difficulty breathing

Question 23

Cholinergic drugs ex direct acting

Answer 23

Bethanechol

Question 24

Indirect acting cholinergic drugs ex

Answer 24

Edrophonium, guanidine, pyridostigamine