urinary incontinence Flashcards
1
Q
what antimuscarinics are given for urinary incontinence - Overa ctiver bladder, urge incontinence!
A
oxybutinin
tolteradine
solifenacin
2
Q
MOA of antimuscarinics for urinary incontinence
A
- competitive inhibitors of ach on musc receptors
- contraction of SM bladder is usually parasympathetic . so blocking - relaxes the bladder, increasing capacity.
- antagonism of m3 receptors - main in bladder
- solifenacin more selctive for m3r so less SE
3
Q
SE antimuscarinics for urinary incotinence
A
- dry mouth
- tachycardia
- constipation
- blurred vision
- urinary retention if bladder outflow obstruction
4
Q
CI to antimuscarinics for urinary incontinence
A
- UTI
caution in
- elderly and dementia due to possible drowsiness and confusion
- angle closure glaucoma - increase IOP
- arrhythmias
- urinary retention isk
5
Q
interactions of antimch for urinary incontinence
A
- TCA, and other antimchs
6
Q
usual dose of oxybutnin
A
5mg oral 8/12 hrly
