anaphylaxis

Question 1

indications for adrenaline

Answer 1

• cardiac arrest; part of ALS
• anaphylaxis
• prolong local anaesthesia; causes local vasoconstriction e.g. in controlling mucosal bleeding

Question 2

MOA of adrenaline

Answer 2

agonist of alpha1,2 and beta 1,2. = stimulates sympathetic nervous system. = vasoconstriction, bronchodilataion

Question 3

SE adrenaline

Answer 3

• after restoration of flow in cardiac arrest = adrenaline induced hypertension

in conscious patients for anaphylaxis;

• anxiety
• tremor
• headache
• palpitaitons

if pre existing heart diseease; MI, Angina, arrhythmias

Question 4

CI to adrenaline

Answer 4

• none in cardiac arrest and anaphylaxis
• if local vasconstriction use; caution in heart disease patients.
• do not use combo adrenalien anesthetics preparations in areas supplied by an end artery. e.g. fingers and toes - necrosis due to constriction

Question 5

interactions of adrenaline

Answer 5

• beta blocker; combined can cause widespread constriction

Question 6

when do you give adrenaline in cardiac arrest

Answer 6

• pre filled syrince = 1:10000 (1mg in 10ml) then flush.
• in VF or pulseless ventricular tachycardia. 1mg IV after 3rd shock and repeat every 3-5 minutes after.
• in asystole or pulseless akak non shockable - give as soon as IV access - adrenaline 1mg IC and repeat every 5mints

Question 7

dose of adrenaline in anaphylaxis

Answer 7

• depends if adult or kid but adult adrenaline 500mcg IM repeated after 5mins if need be. NOT IV unless cardiac arrest too.

dose - 0.5ml of 1:1000 (1mg in 1ml)

Question 8

dose of adrenaline in local cosntriction

Answer 8

ready mixed anaesthetic and adrenaline prep - adrenaline at conc of 1:200000 (5mcg/ml)