bowel prep

Question 1

osmotic laxatives names

Answer 1

lactulose
macrogol
phosphate enema

Question 2

osmotic laxatives Indications

Answer 2

• Constipation and faecal impaction
• bowel prep prior to surgery or endoscopy
• hepatic encephalopathy

Question 3

osmotic laxatives MOA

Answer 3

• osmotically active and remain in gut lumen. hold water in stool maintaining volume and stimualting peristalsis
• lactulose also reduces ammonia absoprtion - by increasing gut transit and acidifying stool.

Question 4

SE osmotic laxatives

Answer 4

• flatulence
• abdo cramps
• nausea
• diarrhoea

phosphate enemas = local irritation and electrolyte disturbances

Question 5

CI osmotic laxative

Answer 5

• intestinal obstruction as may perforate.

Question 6

relative CI to osmotic laxative

Answer 6

• phosphate enema can cause fluid shifts so relative CI In - HF, Ascites, electrolyte disturbances