diarrhoea Flashcards
1
Q
name some antimotility drugs
A
loperamide, codeine phosphate
2
Q
indications of antimotility drugs
A
diarrhoea
3
Q
MOA antimotility drugs
A
- loperimide, opioid similar to pethidine but does not cross BBB. agonist of mew receptors in gut - increases non propulsive contraction but reduces peristaltcic contractions. = slow bowel transit and anal sphincter tone increased
4
Q
SE loperamide
A
- GI effects; flatulance, abdo cramps, constipation
5
Q
codeine phosphate SE
A
- opioid toxicity and dependance risk
6
Q
when to avoid loperamide
A
UC - increased risk of perforation and megacolon
- c diff
- not use in acute bloody diarrhoea aka dysentery esp as can cause HUS
-
7
Q
normal dose loepramide
A
4mg, then 2mg with each loose stool to max of 8mg/day (4 tabls)
8
Q
artificial tears indications
A
- dry eye conditions e.g. keratoconjunctivitis sicca, sjogrens
9
Q
artificial tears MOA
A
- Sooth and protect from abrasions.
can get as drops = cellulose polymer - or as gel = higher viscosity and last longer
- or ointment = paraffin = highly viscous
10
Q
SE artificial tears
A
- mild stinging
- temp blur of vision - more with increased viscosity solutions
- local allergic reaction
11
Q
eye drops dose
A
1-2 drops TDS, can use more but if needed go for more viscose prep
12
Q
gel eye lube dose
A
- 1 drop TDS as needed
13
Q
ointment dose
A
- before bed OD as can cause blurring of vision
14
Q
how to prescribe eye lubes in pallaitive care
A
eye drops One drop per eye 4hrly
