asthma Flashcards
1
Q
name some antimuscarinic bronchodilators
A
ipratropium, triotropium, glycopyrronium, aclidinium
2
Q
indications of antimuscarinic bronchodilators
A
- in COPD - LAMA
2. Asthma - SAMA. or LAMA
3
Q
MOA antimuscarinic bronchodialtors
A
- competitive inhibitors of ach
= stimulating receptors = rest and digest effects. when blocked by these drugs = increase HR and conduction but reduce SM tone and reduce secretions from resp glands and GI tract - in eye - relaxation of pupillary constrictor and ciliary muscles = dilatation and stops accomodation
4
Q
SE antimuscarinic bronchodialtors
A
- irritation of resp tract = nasopharyngitis, sinusitis and cough
- GI disturbance - dry mouth, consitpated, urine retention, blurry vision, headache
5
Q
Cautionary use of antimuscarinic bronchodilators in which patients
A
- angle closure glaucoma = increase IOP
- pt with arrhythmua risk
- pt with urianry retention
6
Q
B2 agonists examples
A
- salbutomol
- terbutaline
- salmeterol
- formeterol
- indaceterol
7
Q
b2 agonist indications
A
- asthma
- COPD
- hyperkalaemia
8
Q
MOA b2 agonists
A
- smooth msucle relaxation.
- stimulat na+/k+ atpase = intracellular shift of k+
9
Q
SE b2 agonists
A
- fight or flight; palpitations, tachycardia, anxiety, tremor
- promote glycogenolysis = increase glucose.
- increase lactate at high doses
- laba = muscle cramps
10
Q
warnings for LABA use in asthma
A
- do not use alone. must be with steroid therapy or icnreased risk of death
11
Q
caution use of b2 agonists in which patients
A
- CVD
12
Q
what shouldr drive nebs in asthma
A
oxygen
13
Q
what should drive nebs in copd
A
air
14
Q
inhaled steroids name some
A
beclometasone
budesonide
fluticasone
15
Q
indications doe inhaled steroids
A
- asthma
2. COPD
