complicated infections

Question 1

name cephalosporins and carbapenems

Answer 1

cefalexin
cefotaxime
meropenem
ertapenem

Question 2

cephalosporins and carbapenems interactions

Answer 2

2nd and 3rd line for UTI and resp infections

- parenteral for severe/ complicated/ antibiotic resistant

Question 3

spectrum of cephalosporin and carbapenems

Answer 3

• broad

- 3rd gen ceph better for pseudomonas

Question 4

MOA cephalosporins and carbapenems

Answer 4

• bactericidal due to beta lactam ring. inhibition of cross linking of cell wall - lysis and death

Question 5

SE cephalosporins and carbapenems

Answer 5

• GI upset
• C diss
• hypersensitivity esp if already to pens - cross reactive
• neuro toxicity inc seziures esp if carbapeneems at high dose or to renal impairment patients

Question 6

CI to cephs and carba

Answer 6

• anaphylaxis
• allergy to pen or themselbes

relative

• risk of C diff
• renal impaired
• epilepsy

Question 7

interactions of cephs and carbs

Answer 7

• enhance effect of warfaring by killing gut flora making vit k.
• increase nephrotoxicity of aminoglycosides
• carbs - reduce efficacy and conc of valproate

Question 8

how can you administer carbs

Answer 8

• IV only inject/infuse