UC Flashcards
mucosal or transmural
mucosal
whichbaprt of the GI tract does it effect
rectum extending proximally
what T cells are involved
Th1 and Th2
smoking effect
dec inflammation
histology
pseudopolyps cryptitis crypt abscesses dec number of mucus cells in glands inc in chronic inflammatory cells in the lamina propria
wall
thinned and loss of haustra
what is the disease called if it is confined to the rectum
proctitis
symptoms
bloody and mucus diarrhoea
night rising
weight loss
lower abdominal pain
inc bowel frequency
proctitis is characterised by
passage of blood and mucus, inc frequency and tenesmus
effect on eyes
uveitis
complications
PSC toxic megacolon colorectal cancer blood loss electrolyte disturbances
toxic megacolon
persistent inflammation causes loss of muscle tone leading to distension
seen in mouth
apthous ulcer
investigations
endoscopy with mucosal biopsy is gold standard
AXR to query toxic megacolon
what will blood thing test show
inc CRP dec Hb and albumin
what may be pANCA be
positive - PSC
what is seen on AXR
thumb printing
mucosal islands
in toxic megacolon what is seen on AXR
mucosal islands
how is severe UC defined
> 6 blood stools a day and 1 of
- fever
- tachycardia
- anaemia
- elevated ESR
what criteria is severe UC defined with
true love and witt
can surgery cure
yes
surgery
proctolectomy with end ileostomy or ileorectal anastomosis
