UC

Question 1

mucosal or transmural

Answer 1

mucosal

Question 2

whichbaprt of the GI tract does it effect

Answer 2

rectum extending proximally

Question 3

what T cells are involved

Answer 3

Th1 and Th2

Question 4

smoking effect

Answer 4

dec inflammation

Question 5

histology

Answer 5

pseudopolyps cryptitis crypt abscesses dec number of mucus cells in glands inc in chronic inflammatory cells in the lamina propria

Question 6

wall

Answer 6

thinned and loss of haustra

Question 7

what is the disease called if it is confined to the rectum

Answer 7

proctitis

Question 8

symptoms

Answer 8

bloody and mucus diarrhoea

night rising

weight loss

lower abdominal pain

inc bowel frequency

Question 9

proctitis is characterised by

Answer 9

passage of blood and mucus, inc frequency and tenesmus

Question 10

effect on eyes

Answer 10

uveitis

Question 11

complications

Answer 11

PSC toxic megacolon colorectal cancer blood loss electrolyte disturbances

Question 12

toxic megacolon

Answer 12

persistent inflammation causes loss of muscle tone leading to distension

Question 13

seen in mouth

Answer 13

apthous ulcer

Question 14

investigations

Answer 14

endoscopy with mucosal biopsy is gold standard

AXR to query toxic megacolon

Question 15

what will blood thing test show

Answer 15

inc CRP dec Hb and albumin

Question 16

what may be pANCA be

Answer 16

positive - PSC

Question 17

what is seen on AXR

Answer 17

thumb printing

mucosal islands

Question 18

in toxic megacolon what is seen on AXR

Answer 18

mucosal islands

Question 19

how is severe UC defined

Answer 19

> 6 blood stools a day and 1 of

• fever
• tachycardia
• anaemia
• elevated ESR

Question 20

what criteria is severe UC defined with

Answer 20

true love and witt

Question 21

can surgery cure

Answer 21

yes

Question 22

surgery

Answer 22

proctolectomy with end ileostomy or ileorectal anastomosis