biliary tract and gallbladder Flashcards

1
Q

gallstone are more common in

A

women

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2
Q

how can crohns lead to gallstones

A

cause bile salt loss

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3
Q

gallstone pathophysiology

A

if the concentrations of bile vary gallstones may form

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4
Q

cholesterol stones

A

formed by crystallisation of cholesterol in micelle surface - cholesterol precipitated out of bile to form solid stones

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5
Q

5 F for gallstones

A
female 
fair 
fat 
forty 
fertile
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6
Q

causes of cholesterol gallstones

A

bile supersaturated with cholesterol - excess cholesterol
not enough bile acids ro salts
gallbladder stasis or inactivity

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7
Q

can cholesterol be seen on XR

A

no - radiolucent

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8
Q

pigment stones

A

excess bilirubin combines with calcium

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9
Q

are pigment stones seen on XR

A

yes - calcium

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10
Q

how do pigment stones form

A

excess bilirubin due to excess haemolytic e.g. haemolytic anaemia

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11
Q

management of gallstones

A

MRCP to view

ERCP to remove

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12
Q

if gallstones effect the CBD what happens

A

jaundice, itch, nausea, anorexia

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13
Q

Cholecystitis

A

inflammation of the gallbladder

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14
Q

what is Cholecystitis usually associated with

A

gallstones lodged in cystic duct

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15
Q

clinical features of Cholecystitis

A

pain - midepigastric. can lead to nausea and vomiting
pain can radiate to right shoulder and RUQ
murphys sign positive

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16
Q

acute Cholecystitis

A

Gallstones obstructing outflow of bile and subsequent infection

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17
Q

acute Cholecystitis CF

A

fever, inc WCC, RUQ pain

18
Q

chronic Cholecystitis

A

chronic inflammation with/out colic

19
Q

chronic Cholecystitis CF

A

flatulence, fat intolerance

20
Q

Cholecystitis treatment

A

IV antibiotics/fluid
NJ nil by mouth
US to confirm
urgent cholecystectomy

21
Q

biliary colic

A

a symptom of gallstones

gallstone lodged in bile duct

22
Q

biliary colic CF

A

RUQ pain - radiate to back or shoulder

no fever, WCC, or jaundice

23
Q

biliary colic pain

A

typically inc for 15 min and then sustain for 6 hours till gallstone dislodges

24
Q

biliary colic diagnosis confirmed by

25
biliary colic treatment
cholecystectomy
26
gallstone ileus
Repeated cholecystitis causes cholecystoenteric fistula to form. Gallstone becomes lodged in small bowel via cholecystoenteric fistula. move down small bowel causing intermittent colic and tends to get stuck at ileum or ileocaecal valve causing obstruction
27
gallstone ileus CF
nausea and indigestion | abdominal distension
28
gallstone ileus treatment
urgent laparotomy - SB enterotomy to remove stone
29
gallbladder adenocarcinoma prognosis
poor as often isn't caught till later stages
30
gallbladder cancer Treatment
cholecystectomy
31
Cholangiocarcinoma
adenocarcinoma
32
Cholangiocarcinoma CF
obstructive jaundice
33
Cholangiocarcinoma investigation
duplex US CT MRCP
34
Cholangiocarcinoma palliative treatment
biliary stent
35
Cholangiocarcinoma cure
surgical resection - whipples
36
what happens if gallstone migrate into CBD
jaudice, itch, nausea and anorexia cholangitis acute pancreatitis
37
what are the CF of ascending cholangitis
pale stools and dark urine charcots triangle pruritis
38
charcots triangle
jaundice, fever and RUQ pain
39
investigations for ascending cholangitis
FBC, UandE, CRP | obstructive jaundice
40
ascending cholangitis treatment
ERCP removal, sphincterotomy or stenting | laparoscopic cholecystectomy