biochemistry of the liver

Question 1

function of alpha globulins

Answer 1

transport lipoproteins, lipids, hormones and bilirubin

also ceruloplasmin

Question 2

what type of globulin is retinal binding protein

Answer 2

alpha

Question 3

what does rental binding protein do

Answer 3

transport vitamin A

converted to retinaldehyde, a visual pigment

Question 4

what does vitamin A deficiency cause

Answer 4

visual impairment

Question 5

name two beta globulin

Answer 5

transferrin and fibrinogen

Question 6

what does transferrin do

Answer 6

transport ferric ion

Question 7

what is transferring an indicator of

Answer 7

iron deficiency

Question 8

what is fibronogen an inactive form of

Answer 8

fibrin

Question 9

most abundant plasma protein

Answer 9

albumin

Question 10

what is the main determinant of plasma oncotic pressure

Answer 10

albumin

Question 11

what effect does insulin have on albumin

Answer 11

stimulate production

Question 12

what is the transport function go albumin

Answer 12

has multiple binding sites for hydrophobic molecules

Question 13

what endogenous substances does albumin transport

Answer 13

fatty acids
bilirubin
thyroid hormones

Question 14

what exogenous substances does albumin transport

Answer 14

drugs like aspirin

Question 15

how is iron transported

Answer 15

ferric ion bound to transferrin

Question 16

how’s iron stored

Answer 16

in cells bound to ferritin

Question 17

how is copper transported in the blood

Answer 17

bound to ceruloplasmin

Question 18

what does ceruloplasmin deficiency cause

Answer 18

wilsons disease - excess copper which accumulates in the liver and brain

Question 19

are steroid hormones and T3 and T4 thyroid hormones hydrophilic or hydrophobic

Answer 19

hydrophobic

Question 20

how are hormones transported in the body

Answer 20

bound to specific transport molecules (self explanatory names)

Question 21

What do the specific transport molecules for hormones do to them

Answer 21

inc their half life and inc plasma concentration (they would be rapidly eliminated from the kidneys or liver without the transport proteins)

Question 22

what does HMG-CoA reductase catalyse the formation of

Answer 22

mevalonic acid (irreversible)

Question 23

what effect does fasting have on HMG - Co A reductase

Answer 23

stimulate

Question 24

most abundant form of vitamin D in the circulatory system

Answer 24

D3

Question 25

3 places that synthesise steroid hormones

Answer 25

ovary
testes
adrenal cortex