NAFLD Flashcards
1
Q
NAFLD
A
inc fat in hepatocytes with/out inflammation
2
Q
outline the progression
A
steatosis - NASH - firbosis - cirrhosis
3
Q
what is simple steatosis
A
just fat
4
Q
what is NASH
A
fat and inflammation
5
Q
histology
A
oxidative stress injury leads to lipid peroxidation in the presence of fatty infiltration and inflammation results, fibrosis may then occur
6
Q
what is fibrosis enhanced by
A
insulin resistance
7
Q
when would one consier NAFLD
A
if they drink less than 18 units per week (9 in women)
8
Q
which individuals does it typically affect
A
those with metabolic syndrome
9
Q
5 parts of metabolic syndrome
A
o Obesity o Hypertension o Diabetes o Hypertriglyceraemia o Hyperlipidaemia
10
Q
ALT
A
asymptomatic rise
around 100-150
11
Q
typical patient
A
middle aged obese female
12
Q
treatment
A
weight loss and exercise
13
Q
how do we diagnose steatosis
A
US
14
Q
how do we diagnose NASH
A
biopsy
