jaundice Flashcards
pre hepatic jaundice
too much haem breakdown
causes of pre hepatic jaundice
haemolytic anaemia rifampicin malaria newborn trauma HUS
what is gilberts
a cause of pre hepatic jaundice
hepatic jaundice
liver cells injured or dead - defect in conjugation of bilirubin within the lier due to hepatocellular damage
hepatic jaundice causes
pregnancy acute liver failure hepatitis - all types cirrhoses bile duct loss
post hepatic jaundice
bile cant escape out into liver
post hepatic jaundice causes
Obstruction of the bile flow out of the liver (cholestasis), causes dilated bile ducts and the backflow of bile.
o Congenital biliary atresia
o Gallstones block common bile duct – pain
o Strictures of common bile duct
o Tumours (head of pancreas)
o Schistosomiasis
what may the liver be like in hepatic jaundice
tender and enlarged
what may the patient be like in post hepatic jaundice
itching and pale stools
tests in pre hepatic
normal
total and unconjugated bilirubin may be raised
bilirubin in hepatic
total, conjugated and unconjugated bilirubin raised
urine and stools in hepatic
dark urine and pale stool
ALP ALT + AST in hepatic
raised
bilirubin in post hepatic
total and conjugated bilirubin raised
unconjugated bilirubin normal
urine adn stools in post hepatic
dark urine and pale stool
